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Literature summary for 3.6.5.2 extracted from

  • Feng, Y.; Ma, M.; Zhang, X.; Liu, D.; Wang, L.; Qian, C.; Wei, G.; Zhu, B.
    Characterization of small GTPase Rac1 and its interaction with PAK1 in crayfish Procambarus clarkii (2019), Fish Shellfish Immunol., 87, 178-183 .
    View publication on PubMed
Search for more literature for 3.6.5.2

Cloned(Commentary)

Cloned (Comment) Organism
gene rac1, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, real-time PCR enzyme expression analysis Procambarus clarkii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Procambarus clarkii Rac1 can interact with the PBD domain of p21-activated kinase 1 (PAK1) ?
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Organism

Organism UniProt Comment Textmining
Procambarus clarkii
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 collected from the Hupo market in Hefei, China
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Source Tissue

Source Tissue Comment Organism Textmining
gill
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 Procambarus clarkii
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heart
-
 Procambarus clarkii
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hemocyte highest expression level Procambarus clarkii
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hepatopancreas lowest expression level Procambarus clarkii
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intestine
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 Procambarus clarkii
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additional information Pc-Rac1 is expressed in all examined tissues with the highest expression level in hemocytes Procambarus clarkii
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muscle
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 Procambarus clarkii
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stomach
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 Procambarus clarkii
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information Rac1 can interact with the PBD domain of p21-activated kinase 1 (PAK1) Procambarus clarkii ?
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-

Subunits

Subunits Comment Organism
? x * 21400, about, sequence calculation Procambarus clarkii

Synonyms

Synonyms Comment Organism
Pc-Rac1
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 Procambarus clarkii
Rac1
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 Procambarus clarkii
Ras-related C3 botulinum toxin substrate 1
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 Procambarus clarkii
small GTPase
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 Procambarus clarkii

pI Value

Organism Comment pI Value Maximum pI Value
Procambarus clarkii sequence calculation
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 8.62

Expression

Organism Comment Expression
Procambarus clarkii the transcriptional expression level of Pc-Rac1 is significantly upregulated in hemocytes and hepatopancreas after lipopolysaccharide (LPS) or polyinosinic:polycytidylic acid (poly I:C) induction. Induced expression pattern of Pc-Rac1 in various tissues by immunostimulating challenges up

General Information

General Information Comment Organism
malfunction RNA interference of Pc-Rac1 affects the mRNA expression levels of immune-related genes lectin, Toll, crustin, TNF, ALF and cactus Procambarus clarkii
metabolism Rac1 can interact with the PBD domain of p21-activated kinase 1 (PAK1) Procambarus clarkii
physiological function Pc-Rac1 is involved in the innate immune responses in Procambarus clarkii Procambarus clarkii