Activating Compound | Comment | Organism | Structure |
---|---|---|---|
GTPase activating protein GAP | complex formation with Ran, stimulates intrinsic GTPase activity | Homo sapiens | |
GTPase activating protein GAP | complex formation with Ran, stimulates intrinsic GTPase activity | Saccharomyces cerevisiae |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
expression in Escherichia coli | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nuclear pore complex | RanGTPase activating protein-Ran complex, stimulation of GTP hydrolysis, terminating export | Saccharomyces cerevisiae | - |
- |
nuclear pore complex | cytosolic surface | Saccharomyces cerevisiae | - |
- |
nucleus | - |
Saccharomyces cerevisiae | 5634 | - |
nucleus | RanGTP form, mediates termination of import and initiation of export | Homo sapiens | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | Homo sapiens | - |
GDP + phosphate | - |
ir | |
GTP + H2O | Saccharomyces cerevisiae | - |
GDP + phosphate | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant enzymes, affinity chromatography | Homo sapiens |
recombinant enzymes, affinity chromatography | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
ir | |
GTP + H2O | - |
Saccharomyces cerevisiae | GDP + phosphate | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
Ran | Ras-related, participating in nucleocytoplasmatic transport | Homo sapiens |