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Literature summary for 3.6.5.1 extracted from

  • Traver, S.; Splingard, A.; Gaudriault, G.; De Gunzburg, J.
    The RGS (regulator of G-protein signalling) and GoLoco domains of RGS14 co-operate to regulate Gi-mediated signalling (2004), Biochem. J., 379, 627-632.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.5.1

Activating Compound

Activating Compound Comment Organism Structure
RGS14 protein
-
 Mammalia

Protein Variants

Protein Variants Comment Organism
E92A/N93A RGS14 mutant Mammalia
E92A/N93A/R519F RGS14 mutant Mammalia
GoLoco RGS14 mutant Mammalia
Myr-Pal-GoLoco RGS14 mutant Mammalia
Myr-Pal-GoLoco R519F RGS14 mutant Mammalia
R336L RGS14 mutant Mammalia
R519F RGS14 mutant Mammalia
RGS RGS14 mutant Mammalia
RID-GoLoco RGS14 mutant Mammalia
RID-GoLoco R336L RGS14 mutant Mammalia
RID-GoLoco R519F RGS14 mutant Mammalia

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + H2O Mammalia
-
 GDP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mammalia
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
 Mammalia GDP + phosphate
-
 ?

Subunits

Subunits Comment Organism
heterotrimer Galpha subunit, GDP-bound inactive, GTP-bound active and betagamma dimer Mammalia

Synonyms

Synonyms Comment Organism
GTP phosphohydrolase
-
 Mammalia
heterotrimeric G-protein GTPase
-
 Mammalia