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Literature summary for 3.6.4.B7 extracted from

  • Zhang, C.; Tian, B.; Li, S.; Ao, X.; Dalgaard, K.; Goekce, S.; Liang, Y.; She, Q.
    Genetic manipulation in Sulfolobus islandicus and functional analysis of DNA repair genes (2013), Biochem. Soc. Trans., 41, 405-410.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Sulfolobus islandicus
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-
-

Synonyms

Synonyms Comment Organism
RadA
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Sulfolobus islandicus

General Information

General Information Comment Organism
physiological function the archaeon may not encode a eukarya-type of NER (nucleotide excision repair) pathway because depleting each of the eukaryal NER homologues XPD, XPB and XPF does not impair the DNA repair capacity in their mutants. But among seven homologous recombination proteins, including RadA, Hel308/Hjm, Rad50, Mre11, HerA, NurA and Hjc, only the Hjc nuclease is dispensable for cell viability. Analysis of genetic mechanisms of DNA repair in this model organism, overview Sulfolobus islandicus