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Literature summary for 3.6.4.7 extracted from

  • Pedrosa, A.G.; Francisco, T.; Bicho, D.; Dias, A.F.; Barros-Barbosa, A.; Hagmann, V.; Dodt, G.; Rodrigues, T.A.; Azevedo, J.E.
    Peroxisomal monoubiquitinated PEX5 interacts with the AAA ATPases PEX1 and PEX6 and is unfolded during its dislocation into the cytosol (2018), J. Biol. Chem., 293, 11553-11563 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome
-
Homo sapiens 5777
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Homo sapiens
-
ADP + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
Homo sapiens ADP + phosphate
-
?
additional information the bona fide substrate membrane docking/translocation module-embedded monoubiquitinated PEX5 interacts directly with both enzyme forms PEX1 and PEX6 through its ubiquitin moiety. The PEX5 polypeptide chain is globally unfolded during the ATP-dependent extraction event Homo sapiens ?
-
-

Subunits

Subunits Comment Organism
? x * 104000, PEX6, SDS-PAGE Homo sapiens
? x * 141000, PEX1, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
ATPase associated with diverse cellular activities
-
Homo sapiens
Pex1
-
Homo sapiens
PEX6
-
Homo sapiens