Any feedback?
Literature summary for 3.6.4.7 extracted from
- AWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPase (2012), Traffic, 13, 168-183.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| peroxisome | AWP1 interacts with Pex6 on the peroxisome | Homo sapiens | 5777 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | AWP1 interacts with Pex6 AAA ATPase, but not with Pex1-Pex6 complexes. The ATPase activity of Pex6 modulates its interaction with AWP1 | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | AWP1 interacts with Pex6 AAA ATPase, but not with Pex1-Pex6 complexes. The ATPase activity of Pex6 modulates its interaction with AWP1 | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Pex6 AAA ATPase | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | in fibroblasts from patients defective in Pex1, Pex6 and Pex26, (all of which are required for Pex5 export) Pex5 stability is decreased | Homo sapiens |
| physiological function | results identify AWP1 as a novel cofactor of Pex6 involved in the regulation of Pex5 export during peroxisome biogenesis | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
