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Literature summary for 3.6.4.7 extracted from

  • Platta, H.W.; Debelyy, M.O.; El Magraoui, F.; Erdmann, R.
    The AAA peroxins Pex1p and Pex6p function as dislocases for the ubiquitinated peroxisomal import receptor Pex5p (2008), Biochem. Soc. Trans., 36, 99-104.
    View publication on PubMed
Search for more literature for 3.6.4.7

Application

Application Comment Organism
medicine more than 80% of all patients with Zellweger syndrome, the most severe peroxisome biogenesis disorder, carry mutations in Pex1p or Pex6p Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
cytosol
-
 Saccharomyces cerevisiae 5829
-
peroxisomal membrane
-
 Homo sapiens 5778
-
peroxisomal membrane
-
 Saccharomyces cerevisiae 5778
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Homo sapiens
-
 ADP + phosphate
-
 ir
ATP + H2O Saccharomyces cerevisiae
-
 ADP + phosphate
-
 ir

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Saccharomyces cerevisiae
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Homo sapiens ADP + phosphate
-
 ir
ATP + H2O
-
 Saccharomyces cerevisiae ADP + phosphate
-
 ir

Subunits

Subunits Comment Organism
More Pex1p and Pex6p are believed to form heterohexameric structures Homo sapiens
More Pex1p and Pex6p are believed to form heterohexameric structures Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
PAS1p
-
 Homo sapiens
PAS1p
-
 Saccharomyces cerevisiae
peroxisome-assembly ATPase
-
 Homo sapiens
peroxisome-assembly ATPase
-
 Saccharomyces cerevisiae
Pex1p
-
 Homo sapiens
Pex1p
-
 Saccharomyces cerevisiae
Pex6p
-
 Homo sapiens
Pex6p
-
 Saccharomyces cerevisiae