Application | Comment | Organism |
---|---|---|
medicine | autosomal recessive mutations in the PEX genes cause peroxisome biogenesis disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy and infantile Refsum disease | Mus musculus |
Cloned (Comment) | Organism |
---|---|
a GST fusion protein containing the PEX1 gene encoding residues 3-180, the N-terminal domain, in pGEX-4T3-PRESAT is constructed | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
K174A | mutant, binds with approximately the same affinity and specificity as the wild-type protein | Mus musculus |
R135A | mutant, the conserved arginine surrounded by hydrophobic residues is essential for lipid binding | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
peroxisomal membrane | - |
Mus musculus | 5778 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | Mus musculus | - |
ADP + phosphate | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
using glutathione Sepharose | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | - |
Mus musculus | ADP + phosphate | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
Pex1 | - |
Mus musculus |