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Literature summary for 3.6.4.7 extracted from

  • Fukuda, S.; Shimozawa, N.; Suzuki, Y.; Zhang, Z.; Tomatsu, S.; Tsukamoto, T.; Hashiguchi, N.; Osumi, T.; Masuno, M.; Imaizumi, K.; Kuroki, Y.; Fujiki, Y.; Orii, T.; Kondo, N.
    Human peroxisome assembly factor-2 (PAF-2): a gene responsible for group C peroxisome biogenesis disorder in humans (1996), Am. J. Hum. Genet., 59, 1210-1220.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.4.7

Application

Application Comment Organism
medicine
-
 Cricetulus griseus
medicine
-
 Rattus norvegicus
medicine development of gene therapy, restoring of peroxisome assemblyby gene transfer to fibroblasts of Zellweger syndrome group C patients Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
PCR amplification, full-length human PAF-2 cDNA cloned Homo sapiens
peroxisome assembly factor-2 cloned from rat cDNA Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Cricetulus griseus
-
 ADP + phosphate
-
 ?
ATP + H2O Homo sapiens
-
 ADP + phosphate
-
 ?
ATP + H2O Rattus norvegicus
-
 ADP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Cricetulus griseus
-
 chinese hamster
-
Homo sapiens
-
 human
-
Rattus norvegicus
-
 rat
-

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O = ADP + phosphate an extremely diversified group of enzymes that use the energy of ATP hydrolysis to import and assemble peroxisome components into the organelle. Their molecular masses range from 25 to 600 kDa Cricetulus griseus
a
ATP + H2O = ADP + phosphate an extremely diversified group of enzymes that use the energy of ATP hydrolysis to import and assemble peroxisome components into the organelle. Their molecular masses range from 25 to 600 kDa Homo sapiens
a
ATP + H2O = ADP + phosphate an extremely diversified group of enzymes that use the energy of ATP hydrolysis to import and assemble peroxisome components into the organelle. Their molecular masses range from 25 to 600 kDa Rattus norvegicus
a

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Cricetulus griseus ADP + phosphate
-
 ?
ATP + H2O
-
 Homo sapiens ADP + phosphate
-
 ?
ATP + H2O
-
 Rattus norvegicus ADP + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
PAF-2
-
 Homo sapiens
PAF-2
-
 Rattus norvegicus