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Literature summary for 3.6.4.6 extracted from

  • Monroe, N.; Han, H.; M.D., Gonciarz; Eckert, D.M.; Karren, M.A.; Whitby, F.G.; Sundquist, W.I.; Hill, C.P.
    The oligomeric state of the active Vps4 AAA ATPase (2013), J. Mol. Biol., 426, 510-525.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
Vta1p
-
Saccharomyces cerevisiae
Vta1p
-
Saccharolobus solfataricus

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Saccharomyces cerevisiae
expression in Escherichia coli Saccharolobus solfataricus

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting-drop vapor diffusion at 20°C Saccharolobus solfataricus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
42248
-
2 * 42248, calculated from sequence, the enzyme rapidly interconverts between multiple oligomeric states, it interconverts between dimers and hexamers in the presence of adenosine nucleotides Saccharolobus solfataricus
42248
-
6 * 42248, calculated from sequence, the enzyme rapidly interconverts between multiple oligomeric states, it interconverts between dimers and hexamers in the presence of adenosine nucleotides Saccharolobus solfataricus
245000
-
gel filtration Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q97ZJ7
-
-
Saccharolobus solfataricus P2 Q97ZJ7
-
-
Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Saccharomyces cerevisiae
-
Saccharolobus solfataricus

Subunits

Subunits Comment Organism
dimer 2 * 42248, calculated from sequence, the enzyme rapidly interconverts between multiple oligomeric states, it interconverts between dimers and hexamers in the presence of adenosine nucleotides Saccharolobus solfataricus
dimer the enzyme interconverts between dimers and hexamers in the presence of adenosine nucleotides Saccharomyces cerevisiae
hexamer 6 * 42248, calculated from sequence, the enzyme rapidly interconverts between multiple oligomeric states, it interconverts between dimers and hexamers in the presence of adenosine nucleotides Saccharolobus solfataricus
hexamer the enzyme interconverts between dimers and hexamers in the presence of adenosine nucleotides Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
AAA ATPase Vps4
-
Saccharomyces cerevisiae
AAA ATPase Vps4
-
Saccharolobus solfataricus
Sso0909 locus name Saccharolobus solfataricus
SsoVps4
-
Saccharolobus solfataricus
vacuolar protein sorting 4
-
Saccharomyces cerevisiae
vacuolar protein sorting 4
-
Saccharolobus solfataricus

General Information

General Information Comment Organism
physiological function the enzyme provides energy for the ESCRT (endosomal sorting complexes required for transport) pathway Saccharolobus solfataricus