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Literature summary for 3.6.4.10 extracted from

  • Wegele, H.; Wandinger, S.K.; Schmid, A.B.; Reinstein, J.; Buchner, J.
    Substrate transfer from the chaperone Hsp70 to Hsp90 (2006), J. Mol. Biol., 356, 802-811.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Homo sapiens Hsp70 together with the two effector proteins Ydj1 and Sti1 exhibits chaperone activity towards luciferase. Sti1/Hop is essential for the transfer of non-native proteins from Hsp70 to Hsp90 ADP + phosphate
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O Hsp70 together with the two effector proteins Ydj1 and Sti1 exhibits chaperone activity towards luciferase. Sti1/Hop is essential for the transfer of non-native proteins from Hsp70 to Hsp90 Homo sapiens ADP + phosphate
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?

Synonyms

Synonyms Comment Organism
Hsp70
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Homo sapiens