Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
additional information | - |
the isolated beta-subdomain,a DnaK substrate-binding domain fragment retaining a portion of the alpha-helical subdomain but harboring mutations that abrogate self-binding is well folded and stable in the empty state and binds peptides with high affinity. When this stable substrate-binding domain and the native ATPase domain are linked in a two-domain construct, the protein is allosterically functional. The two domains of the two-domain construct do not interact, even in the presence of peptide. Nucleotide is necessary to establish allosteric signaling between the domains | Escherichia coli |
Organism | UniProt | Comment | Textmining |
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Escherichia coli | - |
- |
- |
Synonyms | Comment | Organism |
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Hsp70 | - |
Escherichia coli |