Literature summary for 3.6.4.10 extracted from

Brough, P.A.; Barril, X.; Beswick, M.; Dymock, B.W.; Drysdale, M.J.; Wright, L.; Grant, K.; Massey, A.; Surgenor, A.; Workman, P.
3-(5-Chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as inhibitors of the Hsp90 molecular chaperone (2005), Bioorg. Med. Chem. Lett., 15, 5197-5201.

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Inhibitors

Inhibitors	Comment	Organism	Structure
3-(5-chloro-2,4-dihydroxyphenyl)-N-(4-fluorophenyl)-4H-pyrazole-4-carboxamide	-	Homo sapiens
3-(5-chloro-2,4-dihydroxyphenyl)-N-(4-methoxyphenyl)-4H-pyrazole-4-carboxamide	-	Homo sapiens
3-(5-chloro-2,4-dihydroxyphenyl)-N-[3-(trifluoromethyl)phenyl]-4H-pyrazole-4-carboxamide	-	Homo sapiens
N-(4-acetylphenyl)-3-(5-chloro-2,4-dihydroxyphenyl)-4H-pyrazole-4-carboxamide	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
Hsp90alpha	-	Homo sapiens

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Release 2023.1 (January 2023)