Cloned (Comment) | Organism |
---|---|
pT7-mBiP containing the cDNA sequence encoding mature mouse BiP cloned and expressed in Escherichia coli BL21 | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0004 | - |
ATP | - |
Mus musculus | |
0.67 | - |
ATP | - |
Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | hsc70 | Bos taurus | 5829 | - |
endoplasmic reticulum | Hsp70 | Bos taurus | 5783 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30000 | - |
1 * 44000 + 1 * 30000 | Bos taurus |
44000 | - |
1 * 44000 + 1 * 30000 | Bos taurus |
70000 | - |
- |
Bos taurus |
78000 | - |
grp78/BiP | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | Cricetulus griseus | - |
ADP + phosphate | - |
? | |
ATP + H2O | Mus musculus | - |
ADP + phosphate | - |
? | |
ATP + H2O | Bos taurus | - |
ADP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Cricetulus griseus | - |
chinese hamster | - |
Mus musculus | - |
mouse | - |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
recombinant murine BiP, expressed in Escherichia coli | Mus musculus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Cricetulus griseus | |
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Mus musculus | |
ATP + H2O = ADP + phosphate | highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | - |
Cricetulus griseus | ADP + phosphate | - |
? | |
ATP + H2O | - |
Mus musculus | ADP + phosphate | - |
? | |
ATP + H2O | - |
Bos taurus | ADP + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 1 * 44000 + 1 * 30000 | Bos taurus |
Synonyms | Comment | Organism |
---|---|---|
BiP | - |
Cricetulus griseus |
BiP | - |
Bos taurus |
Grp78 | - |
Cricetulus griseus |
Grp78 | - |
Bos taurus |
Hsp70 | - |
Bos taurus |
molecular chaperone BiP | - |
Bos taurus |