Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | at 0.5 mM, EDTA greatly reduces the catalytic activity | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | I NPP is not further stimulated by the addition of of crescent concentrations of Ca2+ or Mg2+ | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mammary cancer cell | - |
Rattus norvegicus | - |
Walker-256 cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl-5'-TMP + H2O | - |
Rattus norvegicus | 4-nitrophenol + 5'-TMP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
E-NPP | - |
Rattus norvegicus |
NPP 1 | isoform | Rattus norvegicus |
NPP 2 | isoform | Rattus norvegicus |
NPP 3 | isoform | Rattus norvegicus |
nucleotide pyrophosphatase/phosphodiesterases | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | the mRNA expression in the cells of the ascitic form of Walker 256 tumor reveals transcripts for isoforms NPP2 and NPP3, whereas elevated expression of NPP3 is observed in solid tumor, after 6, 10, and 15 days of inoculation | up |
General Information | Comment | Organism |
---|---|---|
physiological function | isozyme NPP 3 is important for tumor development, once it is more expressed in solid tumor when compared with the ascitic form | Rattus norvegicus |