Literature summary for 3.6.1.62 extracted from

Burgess, H.M.; Pourchet, A.; Hajdu, C.H.; Chiriboga, L.; Frey, A.B.; Mohr, I.
Targeting poxvirus decapping enzymes and mRNA decay to generate an effective oncolytic virus (2018), Mol. Ther. Oncolytics, 8, 71-81 .

Search for more literature for 3.6.1.62

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
a 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] + H2O	Vaccinia virus	-	N7-methylguanosine 5'-diphosphate + a 5'-phospho-[mRNA]	-	?

Organism

Organism	UniProt	Comment	Textmining
Vaccinia virus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
a 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] + H2O	-	Vaccinia virus	N7-methylguanosine 5'-diphosphate + a 5'-phospho-[mRNA]	-	?

Synonyms

Synonyms	Comment	Organism
mRNA decapping enzyme D10	-	Vaccinia virus
mRNA decapping enzyme D9	-	Vaccinia virus

General Information

General Information	Comment	Organism
malfunction	enzyme-deficient viruses are attenuated in mice. Decapping-deficient vaccinia virus also potently reduces tumor growth in a human hepatocellular carcinoma xenograft model	Vaccinia virus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)