Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
m7G5'ppp5'-mRNA + H2O | Homo sapiens | mRNA decapping is a critical step in the control of mRNA stability and gene expression | m7GDP + 5'-phospho-mRNA | - |
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Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
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Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
m7G5'ppp5'-mRNA + H2O | mRNA decapping is a critical step in the control of mRNA stability and gene expression | Homo sapiens | m7GDP + 5'-phospho-mRNA | - |
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m7G5'ppp5'-mRNA + H2O | a 60 nucleotide element at the 5' end of the mRNA encoding Rrp41 is preferentially bound and decapped by Dcp2. Enhanced decapping of this element is dependent on the structural integrity of its first 33 nt and not its primary sequence. The structure consists of a stem-loop positioned <10 nt from the 5' end of the mRNA | Homo sapiens | m7GDP + 5'-phospho-mRNA | - |
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General Information | Comment | Organism |
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physiological function | mRNA decapping is a critical step in the control of mRNA stability and gene expression | Homo sapiens |