Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
7-methylguanosine 5'-diphosphate + H2O | Saccharomyces cerevisiae | mRNA degradation occurs through distinct pathways, one primarily from the 5' end of the mRNA and the second from the 3' end. Decay from the 3' end generates the m7G5'ppp5'N cap dinucleotide, which is subsequently hydrolyzed to m7Gp and nucleotidyl 5'-diphosphate in Saccharomyces cerevisiae by a scavenger decapping activity termed Dcs1p | 7-methylguanosine 5'-phosphate + phosphate | - |
? | |
m7G5'ppp5'N(3'ppp5'N)n + H2O | Saccharomyces cerevisiae | n = 1-8, mRNA degradation occurs through distinct pathways, one primarily from the 5' end of the mRNA and the second from the 3' end. Decay from the 3' end generates the m7GpppN cap dinucleotide, which is subsequently hydrolyzed to m7Gp and ppN in Saccharomyces cerevisiae by a scavenger decapping activity termed Dcs1p | 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | Q06151 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
7-methylguanosine 5'-diphosphate + H2O | mRNA degradation occurs through distinct pathways, one primarily from the 5' end of the mRNA and the second from the 3' end. Decay from the 3' end generates the m7G5'ppp5'N cap dinucleotide, which is subsequently hydrolyzed to m7Gp and nucleotidyl 5'-diphosphate in Saccharomyces cerevisiae by a scavenger decapping activity termed Dcs1p | Saccharomyces cerevisiae | 7-methylguanosine 5'-phosphate + phosphate | - |
? | |
7-methylguanosine 5'-diphosphate + nucleotidyl 5'-diphosphate + H2O | - |
Saccharomyces cerevisiae | 7-methylguanosine 5'-phosphate + ? | - |
? | |
m7G5'ppp5'N(3'ppp5'N)n + H2O | n = 1-8 | Saccharomyces cerevisiae | 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n | - |
? | |
m7G5'ppp5'N(3'ppp5'N)n + H2O | n = 1-8, mRNA degradation occurs through distinct pathways, one primarily from the 5' end of the mRNA and the second from the 3' end. Decay from the 3' end generates the m7GpppN cap dinucleotide, which is subsequently hydrolyzed to m7Gp and ppN in Saccharomyces cerevisiae by a scavenger decapping activity termed Dcs1p | Saccharomyces cerevisiae | 7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Dcps | - |
Saccharomyces cerevisiae |
General Information | Comment | Organism |
---|---|---|
malfunction | disruption of the DCS1 gene manifests a threefold increase of the TIF51A mRNA half-life. 5' to 3' exoribonucleolytic activity is impeded in the dcs1DELTAstrain, resulting in the accumulation of uncapped mRNA | Saccharomyces cerevisiae |