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Literature summary for 3.6.1.5 extracted from

  • Paes-Vieira, L.; Gomes-Vieira, A.L.; Meyer-Fernandes, J.R.
    NTPDase activities possible roles on Leishmania spp. infectivity and virulence (2018), Cell Biol. Int., 42, 670-682 .
    View publication on PubMed
Search for more literature for 3.6.1.5

Cloned(Commentary)

Cloned (Comment) Organism
gene LMJF_15_0030, sequence comparisons Leishmania major

Localization

Localization Comment Organism GeneOntology No. Textmining
intracellular
-
 Leishmania major 5622
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GDP + H2O Leishmania major
-
 GMP + phosphate
-
 ir
GTP + H2O Leishmania major
-
 GDP + phosphate
-
 ir

Organism

Organism UniProt Comment Textmining
Leishmania major Q4QFI1
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP + H2O
-
 Leishmania major GMP + phosphate
-
 ir
GTP + H2O
-
 Leishmania major GDP + phosphate
-
 ir

Synonyms

Synonyms Comment Organism
ATP diphosphohydrolase
-
 Leishmania major
LmjF15.0030 locus name Leishmania major
LmNTPDase 1
-
 Leishmania major
NTPD1
-
 Leishmania major
nucleoside triphosphate diphosphohydrolase
-
 Leishmania major

General Information

General Information Comment Organism
evolution nucleoside triphosphate diphosphohydrolases (NTPDases) belong to the GDA1/CD39 protein superfamily, E-NTPDase family. Existence of several isoforms with different specificities with respect to divalent cations (magnesium, calcium, manganese, and zinc) and substrates Leishmania major