Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.6.1.5 extracted from

  • Vandenbeuch, A.; Anderson, C.B.; Parnes, J.; Enjyoji, K.; Robson, S.C.; Finger, T.E.; Kinnamon, S.C.
    Role of the ectonucleotidase NTPDase2 in taste bud function (2013), Proc. Natl. Acad. Sci. USA, 110, 14789-14794.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.5

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Mus musculus 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 2 H2O Mus musculus
-
 AMP + 2 phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus O55026
-
-

Source Tissue

Source Tissue Comment Organism Textmining
taste bud isoform NTPDase2 is the dominant form in taste buds Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 2 H2O
-
 Mus musculus AMP + 2 phosphate
-
 ?

Synonyms

Synonyms Comment Organism
NTPDase2
-
 Mus musculus
nucleoside triphosphate diphosphohydrolase-2
-
 Mus musculus

General Information

General Information Comment Organism
malfunction the excessive levels of extracellular ATP in the enzyme knockout animals desensitize the P2X receptors associated with nerve fibers, thereby depressing taste responses Mus musculus