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Literature summary for 3.6.1.5 extracted from

  • Fenckova, M.; Hobizalova, R.; Fric, Z.F.; Dolezal, T.
    Functional characterization of ecto-5-nucleotidases and apyrases in Drosophila melanogaster (2011), Insect Biochem. Mol. Biol., 41, 956-967.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
-
Drosophila melanogaster 9986
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membrane
-
Drosophila melanogaster 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 2 H2O Drosophila melanogaster CG5276 functions as apyrase converting extracellular ATP to ADP and AMP AMP + 2 phosphate
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
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enzymes NT5E-1 and NT5E-2 encoded by genes CG4827 and CG30104
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Source Tissue

Source Tissue Comment Organism Textmining
S2 cell
-
Drosophila melanogaster
-
testis specific expression of NT5E-2 Drosophila melanogaster
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 2 H2O CG5276 functions as apyrase converting extracellular ATP to ADP and AMP Drosophila melanogaster AMP + 2 phosphate
-
?

Synonyms

Synonyms Comment Organism
ecto-5'-nucleotidase
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Drosophila melanogaster

General Information

General Information Comment Organism
evolution CG5276 belongs to another family of calcium-activated nucleotidases. CG5276 may represent an apyrase related to calcium-activated nucleotidases Drosophila melanogaster
physiological function unlike NT5E-1, NT5E-2 seems to play a specific role in male reproduction since it is expressed more strongly in males than in females and is expressed specifically in testis Drosophila melanogaster