Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.6.1.5 extracted from

  • Uccelletti, D.; Pascoli, A.; Farina, F.; Alberti, A.; Mancini, P.; Hirschberg, C.B.; Palleschi, A.C.
    APY-1, a novel Caenorhabditis elegans apyrase involved in unfolded protein response signalling and stress responses (2008), Mol. Biol. Cell, 19, 1337-1345.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information inactivation of apy-1 function by RNAi increased GFP expression fourfold with respect to control, which reflects an hsp-4 upregulation, indicating that loss of apy-1 may effectively cause endoplasmic reticulum stress Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Homo sapiens 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ activates Homo sapiens
Mg2+ activates Homo sapiens
Mn2+ activates Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + 2 H2O Homo sapiens
-
adenosine + 2 phosphate
-
?
ATP + 2 H2O Homo sapiens
-
AMP + 2 phosphate
-
?
GDP + H2O Homo sapiens
-
GMP + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + 2 H2O
-
Homo sapiens adenosine + 2 phosphate
-
?
ATP + 2 H2O
-
Homo sapiens AMP + 2 phosphate
-
?
GDP + H2O
-
Homo sapiens GMP + phosphate
-
?
additional information APY-1 has also NDPase activity Homo sapiens ?
-
?
UDP + 2 H2O
-
Homo sapiens uridine + 2 phosphate
-
?

Synonyms

Synonyms Comment Organism
APY-1
-
Homo sapiens
Apyrase
-
Homo sapiens