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Literature summary for 3.6.1.5 extracted from

  • Levano-Garcia, J.; Mortara, R.A.; Verjovski-Almeida, S.; DeMarco, R.
    Characterization of Schistosoma mansoni ATPDase2 gene, a novel apyrase family member (2007), Biochem. Biophys. Res. Commun., 352, 384-389.
    View publication on PubMed
Search for more literature for 3.6.1.5

Cloned(Commentary)

Cloned (Comment) Organism
gene encoding ATPDase2, DNA and amino acid sequence determination and analysis, sequence comparison Schistosoma mansoni

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular ATPDase2 is secreted by the worm to the culture medium Schistosoma mansoni
-
-
membrane
-
 Schistosoma mansoni 16020
-
membrane ATPDase2 contains a single N-terminal transmembrane domain Schistosoma mansoni 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + H2O Schistosoma mansoni
-
 AMP + phosphate
-
 ?
ATP + H2O Schistosoma mansoni
-
 ADP + phosphate
-
 ?
additional information Schistosoma mansoni ATPDase2 plays a non-redundant role in the parasite-host interplay ?
-
 ?

Organism

Organism UniProt Comment Textmining
Schistosoma mansoni
-
 BH strain, gene ATPDase1
-
Schistosoma mansoni A1BXT9 ATP-diphosphohydrolase 2; BH strain, gene ATPDase2
-

Source Tissue

Source Tissue Comment Organism Textmining
integument ATPDase1 is located at the external surface of the parasite Schistosoma mansoni
-
additional information ATPDase1 is found in adult worm tegument basal and apical membranes, immunohistochemic localization anaylsis Schistosoma mansoni
-
additional information ATPDase2 is found in adult worm tegument basal and apical membranes, and in the tegument syncytium, immunohistochemic localization anaylsis Schistosoma mansoni
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + H2O
-
 Schistosoma mansoni AMP + phosphate
-
 ?
ATP + H2O
-
 Schistosoma mansoni ADP + phosphate
-
 ?
additional information ATPDase2 plays a non-redundant role in the parasite-host interplay Schistosoma mansoni ?
-
 ?

Synonyms

Synonyms Comment Organism
ATP-diphosphohydrolase 2
-
 Schistosoma mansoni
ATPDase1
-
 Schistosoma mansoni
ATPDase2
-
 Schistosoma mansoni
CD39-like ATP diphosphohydrolase
-
 Schistosoma mansoni
More the enzyme belongs to the apyrase family Schistosoma mansoni