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Literature summary for 3.6.1.5 extracted from

  • Alves-Ferreira, M.; Dutra, P.M.; Lopes, A.H.; Ferreira-Pereira, A.; Scofano, H.M.; Meyer-Fernandes, J.R.
    Magnesium-dependent ecto-ATP diphosphohydrolase activity in Herpetomonas muscarum muscarum (2003), Curr. Microbiol., 47, 265-271.
    View publication on PubMed
Search for more literature for 3.6.1.5

Inhibitors

Inhibitors Comment Organism Structure
5,5'-diisothiocyanato-2,2'-(ethene-1,2-diyl)dibenzenesulfonic acid 0.1 mM, 40% residual activity Herpetomonas muscarum
ADP competitive Herpetomonas muscarum
additional information not inhibitory: sodium orthovanadate, sodium fluoride, ammonium molybdate, oligomycin, sodium azide, bafilomycin A, ouabain, levamizole Herpetomonas muscarum
suramin 0.1 mM, 10% residual activity Herpetomonas muscarum

Metals/Ions

Metals/Ions Comment Organism Structure
MgCl2 5 mM, stimulation up to 20fold, best activating kation Herpetomonas muscarum
MnCl2 5 mM, stimulation up to 10fold Herpetomonas muscarum
ZnCl2 5 mM, stimulation Herpetomonas muscarum

Organism

Organism UniProt Comment Textmining
Herpetomonas muscarum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + H2O 67% of activity compared to ATP Herpetomonas muscarum AMP + phosphate
-
 ?
ATP + 2 H2O
-
 Herpetomonas muscarum AMP + 2 phosphate
-
 ?
additional information no substrate: CTP, CDP, GTP, GDP Herpetomonas muscarum ?
-
 ?
UDP + H2O 31% of activity compared to ATP Herpetomonas muscarum UMP + phosphate
-
 ?
UTP + 2 H2O 25% of activity compared to ATP Herpetomonas muscarum UMP + 2 phosphate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Herpetomonas muscarum