BRENDA - Enzyme Database show
show all sequences of 3.6.1.43

Developmental changes in enzymes involved in dolichyl phosphate metabolism in cultured embryonic rat brain cells

Bhat, N.R.; Frank, D.W.; Wolf, M.J.; Waechter, C.J.; J. Neurochem. 56, 339-344 (1991)

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.025
-
dolichyl diphosphate
day 4 of embryonic development
Rattus norvegicus
0.166
-
dolichyl diphosphate
day 22 of embryonic development
Rattus norvegicus
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
dolichyl diphosphate + H2O
Rattus norvegicus
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
dolichyl phosphate + phosphate
-
Rattus norvegicus
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
brain
embryonic
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
increases significantly during day 12-25 of embryonic development
Rattus norvegicus
0.003
-
day 4 of embryonic development
Rattus norvegicus
0.032
-
day 22 of embryonic development
Rattus norvegicus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
dolichyl diphosphate + H2O
-
134921
Rattus norvegicus
dolichyl phosphate + phosphate
-
134921
Rattus norvegicus
?
dolichyl diphosphate + H2O
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
134921
Rattus norvegicus
dolichyl phosphate + phosphate
-
134921
Rattus norvegicus
?
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.025
-
dolichyl diphosphate
day 4 of embryonic development
Rattus norvegicus
0.166
-
dolichyl diphosphate
day 22 of embryonic development
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
dolichyl diphosphate + H2O
Rattus norvegicus
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
dolichyl phosphate + phosphate
-
Rattus norvegicus
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
brain
embryonic
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
increases significantly during day 12-25 of embryonic development
Rattus norvegicus
0.003
-
day 4 of embryonic development
Rattus norvegicus
0.032
-
day 22 of embryonic development
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
dolichyl diphosphate + H2O
-
134921
Rattus norvegicus
dolichyl phosphate + phosphate
-
134921
Rattus norvegicus
?
dolichyl diphosphate + H2O
involved in biosynthesis of glycoproteins, regeneration of dolichyl phosphate
134921
Rattus norvegicus
dolichyl phosphate + phosphate
-
134921
Rattus norvegicus
?
Other publictions for EC 3.6.1.43
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
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5
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1
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1
1
1
1
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656097
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2
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2
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656027
Fernandez
The CWH8 gene encodes a dolich ...
Saccharomyces cerevisiae
J. Biol. Chem.
276
41455-41464
2001
-
-
1
-
-
1
-
2
2
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3
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1
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2
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1
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1
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1
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2
2
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1
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-
2
-
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-
1
-
-
-
-
-
-
-
-
-
134921
Bhat
Developmental changes in enzym ...
Rattus norvegicus
J. Neurochem.
56
339-344
1991
-
-
-
-
-
-
-
2
-
-
-
1
-
2
-
-
-
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-
1
3
-
2
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2
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1
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1
3
-
2
-
-
-
-
-
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-
289082
Shabalin
-
Intracellular distribution and ...
Saccharomyces cerevisiae
Biochemistry (Moscow)
56
2032-2041
1991
1
-
-
-
-
-
2
-
3
-
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1
-
1
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1
2
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1
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2
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3
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1
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1
2
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289080
Scher
Dolichyl pyrophosphate phospha ...
Bos taurus
Methods Enzymol.
111
547-553
1985
3
-
-
-
-
-
3
-
-
-
-
1
-
1
-
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-
-
-
1
-
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2
-
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-
1
-
-
-
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-
-
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3
-
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3
-
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1
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1
-
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2
-
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1
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-
-
-
-
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-
289079
Scher
Brain dolichyl pyrophosphate p ...
Bos taurus
J. Biol. Chem.
259
14580-14585
1984
4
-
-
-
-
-
9
1
3
2
-
1
-
1
-
-
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-
-
1
1
2
2
-
-
-
1
-
1
-
-
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4
-
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-
-
-
-
-
9
-
1
3
2
-
1
-
-
-
-
-
1
1
2
2
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
134917
Belocopitow
Dolichyl-phosphate phosphatase ...
Rattus norvegicus
Eur. J. Biochem.
125
167-173
1982
1
-
-
-
-
-
7
-
1
1
-
1
-
1
-
-
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-
1
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2
-
1
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1
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1
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7
-
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1
1
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1
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1
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2
-
1
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1
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-
-
-
-
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-
-
289076
Applekvist
-
Dolichol (C55) mono-and pyroph ...
Rattus norvegicus
Biosci. Rep.
1
619-626
1981
1
-
-
-
-
-
3
-
6
1
-
1
-
1
-
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1
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1
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2
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1
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1
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3
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6
1
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1
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1
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1
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2
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1
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-
289077
Boscoboinik
Assay of dolichol monophosphat ...
Rattus norvegicus
Anal. Biochem.
114
42-45
1981
-
-
-
-
-
-
-
-
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1
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1
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1
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1
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134908
Wedgwood
Enzymatic activities in cultur ...
Homo sapiens
J. Biol. Chem.
255
1120-1123
1980
1
-
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-
1
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1
1
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1
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2
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1
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2
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1
1
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1
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1
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1
1
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1
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1
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2
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1
1
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