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Literature summary for 3.6.1.41 extracted from

  • Ismail, T.M.; Hart, C.A.; McLennan, A.G.
    Regulation of dinucleoside polyphosphate pools by the YgdP and ApaH hydrolases Is essential for the ability of Salmonella enterica serovar Typhimurium to invade cultured mammalian cells (2003), J. Biol. Chem., 278, 32602-32607.
    View publication on PubMed
Search for more literature for 3.6.1.41

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli of a His-tagged recombinant protein Salmonella enterica

Protein Variants

Protein Variants Comment Organism
additional information generation of null mutants by replacement of the gene encoding the enzyme with antibiotic resistance cassettes, the resulting STYA201 strain shows reduced ability to invade cultured mammalian cells Salmonella enterica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.014
-
 P1,P6-bis(5'-adenosyl)hexaphosphate reaction medium contains 0.1 mM CoCl2 Salmonella enterica
0.037
-
 P1,P4-bis(5'-adenosyl) tetraphosphate reaction medium contains 0.1 mM CoCl2 Salmonella enterica

Organism

Organism UniProt Comment Textmining
Salmonella enterica
-
 serovar typhimurium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O hydrolysis of Ap4A Salmonella enterica ADP
-
 ?
P1,P6-bis(5'-adenosyl)hexaphosphate + H2O hydrolysis of Ap6A Salmonella enterica ADP + ?
-
 ?

Synonyms

Synonyms Comment Organism
ApaH hydrolase
-
 Salmonella enterica