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Literature summary for 3.6.1.39 extracted from

  • Dahlmann, N.
    A one-step liquid-chromatographic technique for the estimation of the deoxythymidine-5-triphosphatase in human serum (1984), Hoppe-Seyler's Z. Physiol. Chem., 365, 1263-1269.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
dCTP competitive inhibitor with dTTP as substrate, Ki: 0.25 mM Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.04
-
 dTTP
-
 Homo sapiens
0.091
-
 dCTP
-
 Homo sapiens
0.125
-
 dTTP/dCTP equimolar Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24000
-
 SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dTTP + H2O Homo sapiens
-
 dTDP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial purification Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dCTP + H2O
-
 Homo sapiens dCDP + phosphate
-
 ?
dTTP + H2O
-
 Homo sapiens dTDP + phosphate
-
 ?
dTTP/dCTP + H2O
-
 Homo sapiens dTDP/dCDP + phosphate
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.25
-
 dCTP competitive inhibitor with dTTP as substrate Homo sapiens