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Literature summary for 3.6.1.28 extracted from

  • Makarchikov, A.F.; Lakaye, B.; Gulyai, I.E.; Czerniecki, J.; Coumans, B.; Wins, P.; Grisar, T.; Bettendorff, L.
    Thiamine triphosphate and thiamine triphosphatase activities: from bacteria to mammals (2003), Cell. Mol. Life Sci., 60, 1477-1488.
    View publication on PubMed
Search for more literature for 3.6.1.28

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.016
-
 thiamine triphosphate enzyme from brain Rattus norvegicus
0.0201
-
 thiamine triphosphate enzyme from embryonic brain Rattus norvegicus
0.0211
-
 thiamin triphosphate enzyme from liver Bos taurus
0.0228
-
 thiamine triphosphate enzyme from kidney Rattus norvegicus
0.0253
-
 thiamine triphosphate enzyme from embryonic liver Rattus norvegicus
0.0278
-
 thiamine triphosphate enzyme from liver Rattus norvegicus
0.0338
-
 thiamin triphosphate enzyme from spleen Bos taurus
0.0359
-
 thiamin triphosphate enzyme from trapezius Bos taurus
0.0388
-
 thiamin triphosphate enzyme from lung Bos taurus
0.0406
-
 thiamin triphosphate enzyme from heart Bos taurus
0.0441
-
 thiamin triphosphate enzyme from brain Bos taurus
0.0446
-
 thiamin triphosphate enzyme from duodenum Bos taurus
0.0451
-
 thiamin triphosphate enzyme from kidney Bos taurus
0.0495
-
 thiamine triphosphate enzyme from kidney Sus scrofa
0.126
-
 thiamin triphosphate
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
additional information
-
 molecular weight of enzyme from brain and pectoralis muscle is above 80000 Da Gallus gallus
additional information
-
 the molecular weight of the brain enzyme is above 80000 Da quail
25550
-
 gel filtration Homo sapiens
26300
-
 brain enzyme, gel filtration Bos taurus
27200
-
 lung enzyme, gel filtration Bos taurus
27600
-
 trapezius muscle enzyme, gel filtration Bos taurus
28300
-
 kidney enzyme, gel filtration Bos taurus
28400
-
 liver enzyme, gel filtratuon Bos taurus
29000
-
 spleen enzyme, gel filtration Bos taurus
29100
-
 heart enzyme, gel filtration Bos taurus
29700
-
 liver enzyme, gel filtratuon Rattus norvegicus
31000
-
 enzyme from embryo, gel filtration Rattus norvegicus
31700
-
 duodenum enzyme, gel filtration Bos taurus
32000
-
 muscle enzyme, gel filtration Rattus norvegicus
32200
-
 brain enzyme, gel filtration Rattus norvegicus
33900
-
 gel filtration Sus scrofa
34000
-
 kidney enzyme, gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Gallus gallus
-
-
-
Homo sapiens
-
-
-
quail
-
-
-
Rattus norvegicus
-
-
-
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Gallus gallus
-
brain
-
 Rattus norvegicus
-
brain
-
 Sus scrofa
-
brain
-
 quail
-
brain 309 nmol per min per mg of wet weight Bos taurus
-
cerebellum
-
 Homo sapiens
-
duodenum 33 nmol per min per mg of wet weight Bos taurus
-
embryo
-
 Rattus norvegicus
-
heart
-
 quail
-
heart 217 nmol per min per mg of wet weight Bos taurus
-
kidney
-
 Rattus norvegicus
-
kidney
-
 Sus scrofa
-
kidney
-
 quail
-
kidney 377 nmol per min per mg of wet weight Bos taurus
-
liver
-
 Rattus norvegicus
-
liver
-
 quail
-
liver 354 nmol per min per mg of wet weight Bos taurus
-
lung 333 nmol per min per mg of wet weight Bos taurus
-
lymph node 220 nmol per min per mg of wet weight Bos taurus
-
muscle pectoralis Gallus gallus
-
muscle pectoralis quail
-
muscle quadriceps Rattus norvegicus
-
muscle trapezius, 169 nmol per min per mg of wet weight Bos taurus
-
skeletal muscle
-
 Sus scrofa
-
spleen 275 nmol per min per mg of wet weight Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0003
-
 activity in quadriceps quail
0.0006
-
 activity in brain quail
0.0006
-
 activity in heart quail
0.0008
-
 activity in kidney quail
0.0024
-
 activity in liver quail
0.0114
-
 activity in brain Gallus gallus
0.0125
-
 activity in skeletal muscle Sus scrofa
0.0162
-
 activity in kidney Sus scrofa
0.033
-
 duodenum Bos taurus
0.052
-
 activity in quadriceps Rattus norvegicus
0.057
-
 cerebellum Homo sapiens
0.169
-
 trapezius muscle Bos taurus
0.189
-
 activity in kidney Rattus norvegicus
0.217
-
 heart Bos taurus
0.22
-
 lymph node Bos taurus
0.275
-
 spleen Bos taurus
0.299
-
 activity in liver Rattus norvegicus
0.309
-
 brain Bos taurus
0.333
-
 lung Bos taurus
0.354
-
 liver Bos taurus
0.377
-
 kidney Bos taurus
0.437
-
 activity in brain Rattus norvegicus
0.932
-
 activity in pectoralis muscle Gallus gallus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
thiamin triphosphate + H2O
-
 Rattus norvegicus thiamine diphosphate + phosphate
-
 ?
thiamine triphosphate + H2O
-
 Gallus gallus thiamine diphosphate + phosphate
-
 ?
thiamine triphosphate + H2O
-
 Homo sapiens thiamine diphosphate + phosphate
-
 ?
thiamine triphosphate + H2O
-
 Sus scrofa thiamine diphosphate + phosphate
-
 ?
thiamine triphosphate + H2O
-
 Bos taurus thiamine diphosphate + phosphate
-
 ?
thiamine triphosphate + H2O
-
 quail thiamine diphosphate + phosphate
-
 ?