BRENDA - Enzyme Database
show all sequences of 3.6.1.26

Stereospecific synthesis and enzyme studies of CDP-diacylglycerols

Murthy, P.P.N.; Agranoff, B.W.; Biochim. Biophys. Acta 712, 473-483 (1982)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
Triton X-100
detergent required for activity, optimum concentration 0.3%
Cavia porcellus
Inhibitors
Inhibitors
Commentary
Organism
Structure
AMP
none competitive, Ki: 0.04 mM
Cavia porcellus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.04
-
CDP-1-stearoyl-2-oleoylglycerol
-
Cavia porcellus
0.047
-
CDP-1-stearoyl-2-stearoylglycerol
-
Cavia porcellus
0.063
-
CDPdipalmitoylglycerol
-
Cavia porcellus
0.14
-
CDPdistearoylglycerol
-
Cavia porcellus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
lysosome
-
Cavia porcellus
5764
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
CDPdiacylglycerol + H2O
Cavia porcellus
-
CMP + phosphatidate
-
Cavia porcellus
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Cavia porcellus
-
-
-
Purification (Commentary)
Commentary
Organism
-
Cavia porcellus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
brain
-
Cavia porcellus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
CDP-1-stearoyl-2-oleoylglycerol + H2O
-
210005
Cavia porcellus
CMP + 1-stearoyl-2-oleoyl-sn-glycerol-3-phosphate
-
210005
Cavia porcellus
?
CDP-1-stearoyl-2-stearoylglycerol + H2O
-
210005
Cavia porcellus
CMP + 1,2-distearoyl-sn-glycerol-3-phosphate
-
210005
Cavia porcellus
?
CDPdiacylglycerol + H2O
-
210005
Cavia porcellus
CMP + phosphatidate
-
210005
Cavia porcellus
?
CDPdipalmitoylglycerol + H2O
-
210005
Cavia porcellus
CMP + 1,2-dipalmitoyl-sn-glycerol-3-phosphate
-
210005
Cavia porcellus
?
CDPdistearoylglycerol + H2O
-
210005
Cavia porcellus
CMP + 1,2-distearoyl-sn-glycerol-3-phosphate
-
210005
Cavia porcellus
?
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
Triton X-100
detergent required for activity, optimum concentration 0.3%
Cavia porcellus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
AMP
none competitive, Ki: 0.04 mM
Cavia porcellus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.04
-
CDP-1-stearoyl-2-oleoylglycerol
-
Cavia porcellus
0.047
-
CDP-1-stearoyl-2-stearoylglycerol
-
Cavia porcellus
0.063
-
CDPdipalmitoylglycerol
-
Cavia porcellus
0.14
-
CDPdistearoylglycerol
-
Cavia porcellus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
lysosome
-
Cavia porcellus
5764
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
CDPdiacylglycerol + H2O
Cavia porcellus
-
CMP + phosphatidate
-
Cavia porcellus
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Cavia porcellus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
brain
-
Cavia porcellus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
CDP-1-stearoyl-2-oleoylglycerol + H2O
-
210005
Cavia porcellus
CMP + 1-stearoyl-2-oleoyl-sn-glycerol-3-phosphate
-
210005
Cavia porcellus
?
CDP-1-stearoyl-2-stearoylglycerol + H2O
-
210005
Cavia porcellus
CMP + 1,2-distearoyl-sn-glycerol-3-phosphate
-
210005
Cavia porcellus
?
CDPdiacylglycerol + H2O
-
210005
Cavia porcellus
CMP + phosphatidate
-
210005
Cavia porcellus
?
CDPdipalmitoylglycerol + H2O
-
210005
Cavia porcellus
CMP + 1,2-dipalmitoyl-sn-glycerol-3-phosphate
-
210005
Cavia porcellus
?
CDPdistearoylglycerol + H2O
-
210005
Cavia porcellus
CMP + 1,2-distearoyl-sn-glycerol-3-phosphate
-
210005
Cavia porcellus
?
Other publictions for EC 3.6.1.26
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
210005
Murthy
Stereospecific synthesis and e ...
Cavia porcellus
Biochim. Biophys. Acta
712
473-483
1982
1
-
-
-
-
-
1
4
1
-
-
1
-
1
-
-
1
-
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
4
1
-
-
1
-
-
-
1
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210004
Raetz
A membrane-bound pyrophosphata ...
Escherichia coli
J. Biol. Chem.
247
2245-2247
1972
1
-
-
-
-
-
7
-
1
1
-
1
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1
-
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1
-
-
-
-
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1
-
-
-
-
-
-
-
-
-
-
-
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1
-
-
-
-
-
-
-
7
-
-
1
1
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
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-
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