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Literature summary for 3.6.1.26 extracted from
- Stereospecific synthesis and enzyme studies of CDP-diacylglycerols (1982), Biochim. Biophys. Acta, 712, 473-483.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Triton X-100 | detergent required for activity, optimum concentration 0.3% | Cavia porcellus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| AMP | none competitive, Ki: 0.04 mM | Cavia porcellus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.04 | - |
CDP-1-stearoyl-2-oleoylglycerol | - |
Cavia porcellus | |
| 0.047 | - |
CDP-1-stearoyl-2-stearoylglycerol | - |
Cavia porcellus | |
| 0.063 | - |
CDPdipalmitoylglycerol | - |
Cavia porcellus | |
| 0.14 | - |
CDPdistearoylglycerol | - |
Cavia porcellus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Cavia porcellus | 5764 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDPdiacylglycerol + H2O | Cavia porcellus | - |
CMP + phosphatidate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cavia porcellus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Cavia porcellus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Cavia porcellus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-1-stearoyl-2-oleoylglycerol + H2O | - |
Cavia porcellus | CMP + 1-stearoyl-2-oleoyl-sn-glycerol-3-phosphate | - |
? | |
| CDP-1-stearoyl-2-stearoylglycerol + H2O | - |
Cavia porcellus | CMP + 1,2-distearoyl-sn-glycerol-3-phosphate | - |
? | |
| CDPdiacylglycerol + H2O | - |
Cavia porcellus | CMP + phosphatidate | - |
? | |
| CDPdipalmitoylglycerol + H2O | - |
Cavia porcellus | CMP + 1,2-dipalmitoyl-sn-glycerol-3-phosphate | - |
? | |
| CDPdistearoylglycerol + H2O | - |
Cavia porcellus | CMP + 1,2-distearoyl-sn-glycerol-3-phosphate | - |
? | |
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