BRENDA - Enzyme Database
show all sequences of 3.6.1.26

A membrane-bound pyrophosphatase in Escherichia coli catalyzing the hydrolysis of cytidine diphosphate-diglyceride

Raetz, C.R.H.; Hirschberg, C.B.; Dowhan, W.; Wickner, W.T.; Kenney, E.P.; J. Biol. Chem. 247, 2245-2247 (1972)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
Triton X-100
-
Escherichia coli
Inhibitors
Inhibitors
Commentary
Organism
Structure
ADP
-
Escherichia coli
AMP
very strong inhibition
Escherichia coli
ATP
-
Escherichia coli
cAMP
-
Escherichia coli
CMP
no inhibition
Escherichia coli
GMP
-
Escherichia coli
UMP
slight inhibition
Escherichia coli
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
-
Escherichia coli
16020
-
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
additional information
no requirement for added metal ions
Escherichia coli
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
CDPdiacylglycerol + H2O
Escherichia coli
-
CMP + phosphatidate
-
Escherichia coli
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Escherichia coli
-
-
-
Purification (Commentary)
Commentary
Organism
partial
Escherichia coli
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
CDPdiacylglycerol + H2O
-
210004
Escherichia coli
CMP + phosphatidate
-
210004
Escherichia coli
?
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
Triton X-100
-
Escherichia coli
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
ADP
-
Escherichia coli
AMP
very strong inhibition
Escherichia coli
ATP
-
Escherichia coli
cAMP
-
Escherichia coli
CMP
no inhibition
Escherichia coli
GMP
-
Escherichia coli
UMP
slight inhibition
Escherichia coli
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
membrane
-
Escherichia coli
16020
-
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
additional information
no requirement for added metal ions
Escherichia coli
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
CDPdiacylglycerol + H2O
Escherichia coli
-
CMP + phosphatidate
-
Escherichia coli
?
Purification (Commentary) (protein specific)
Commentary
Organism
partial
Escherichia coli
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
CDPdiacylglycerol + H2O
-
210004
Escherichia coli
CMP + phosphatidate
-
210004
Escherichia coli
?
Other publictions for EC 3.6.1.26
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
210005
Murthy
Stereospecific synthesis and e ...
Cavia porcellus
Biochim. Biophys. Acta
712
473-483
1982
1
-
-
-
-
-
1
4
1
-
-
1
-
1
-
-
1
-
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
4
1
-
-
1
-
-
-
1
-
1
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
210004
Raetz
A membrane-bound pyrophosphata ...
Escherichia coli
J. Biol. Chem.
247
2245-2247
1972
1
-
-
-
-
-
7
-
1
1
-
1
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
7
-
-
1
1
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-