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Literature summary for 3.6.1.23 extracted from

  • Galperin, M.Y.; Moroz, O.V.; Wilson, K.S.; Murzin, A.G.
    House cleaning, a part of good housekeeping (2006), Mol. Microbiol., 59, 5-19.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dUTP + H2O Staphylococcus aureus
-
dUMP + diphosphate
-
?
dUTP + H2O Escherichia coli
-
dUMP + diphosphate
-
?
dUTP + H2O Saccharomyces cerevisiae
-
dUMP + diphosphate
-
?
dUTP + H2O Trypanosoma cruzi
-
dUMP + diphosphate
-
?
dUTP + H2O Leishmania major
-
dUMP + diphosphate
-
?
dUTP + H2O Campylobacter jejuni
-
dUMP + diphosphate
-
?
dUTP + H2O Mycobacterium tuberculosis
-
dUMP + diphosphate
-
?
dUTP + H2O Mycobacterium tuberculosis H37Rv
-
dUMP + diphosphate
-
?
additional information Staphylococcus aureus biological functions in housekeeping, overview ?
-
?
additional information Escherichia coli biological functions in housekeeping, overview ?
-
?
additional information Saccharomyces cerevisiae biological functions in housekeeping, overview ?
-
?
additional information Trypanosoma cruzi biological functions in housekeeping, overview ?
-
?
additional information Leishmania major biological functions in housekeeping, overview ?
-
?
additional information Campylobacter jejuni biological functions in housekeeping, overview ?
-
?
additional information Mycobacterium tuberculosis biological functions in housekeeping, overview ?
-
?
additional information Mycobacterium tuberculosis H37Rv biological functions in housekeeping, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
-
-
Escherichia coli
-
-
-
Leishmania major
-
-
-
Mycobacterium tuberculosis P9WNS5
-
-
Mycobacterium tuberculosis H37Rv P9WNS5
-
-
Saccharomyces cerevisiae
-
-
-
Staphylococcus aureus
-
-
-
Trypanosoma cruzi
-
-
-

Reaction

Reaction Comment Organism Reaction ID
dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Staphylococcus aureus
dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Escherichia coli
dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Saccharomyces cerevisiae
dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Trypanosoma cruzi
dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Leishmania major
dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Campylobacter jejuni
dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Mycobacterium tuberculosis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dUTP + H2O
-
Staphylococcus aureus dUMP + diphosphate
-
?
dUTP + H2O
-
Escherichia coli dUMP + diphosphate
-
?
dUTP + H2O
-
Saccharomyces cerevisiae dUMP + diphosphate
-
?
dUTP + H2O
-
Trypanosoma cruzi dUMP + diphosphate
-
?
dUTP + H2O
-
Leishmania major dUMP + diphosphate
-
?
dUTP + H2O
-
Campylobacter jejuni dUMP + diphosphate
-
?
dUTP + H2O
-
Mycobacterium tuberculosis dUMP + diphosphate
-
?
dUTP + H2O
-
Mycobacterium tuberculosis H37Rv dUMP + diphosphate
-
?
additional information biological functions in housekeeping, overview Staphylococcus aureus ?
-
?
additional information biological functions in housekeeping, overview Escherichia coli ?
-
?
additional information biological functions in housekeeping, overview Saccharomyces cerevisiae ?
-
?
additional information biological functions in housekeeping, overview Trypanosoma cruzi ?
-
?
additional information biological functions in housekeeping, overview Leishmania major ?
-
?
additional information biological functions in housekeeping, overview Campylobacter jejuni ?
-
?
additional information biological functions in housekeeping, overview Mycobacterium tuberculosis ?
-
?
additional information substrate specificity, no hydrolysis of canonical NTPs, overview Staphylococcus aureus ?
-
?
additional information substrate specificity, no hydrolysis of canonical NTPs, overview Escherichia coli ?
-
?
additional information substrate specificity, no hydrolysis of canonical NTPs, overview Saccharomyces cerevisiae ?
-
?
additional information substrate specificity, no hydrolysis of canonical NTPs, overview Trypanosoma cruzi ?
-
?
additional information substrate specificity, no hydrolysis of canonical NTPs, overview Leishmania major ?
-
?
additional information substrate specificity, no hydrolysis of canonical NTPs, overview Campylobacter jejuni ?
-
?
additional information substrate specificity, no hydrolysis of canonical NTPs, overview Mycobacterium tuberculosis ?
-
?
additional information biological functions in housekeeping, overview Mycobacterium tuberculosis H37Rv ?
-
?
additional information substrate specificity, no hydrolysis of canonical NTPs, overview Mycobacterium tuberculosis H37Rv ?
-
?

Subunits

Subunits Comment Organism
dimer homodimer Staphylococcus aureus
dimer homodimer Trypanosoma cruzi
dimer homodimer Leishmania major
dimer homodimer Campylobacter jejuni
trimer homotrimer Escherichia coli
trimer homotrimer Saccharomyces cerevisiae
trimer homotrimer Mycobacterium tuberculosis

Synonyms

Synonyms Comment Organism
dUTPase
-
Staphylococcus aureus
dUTPase
-
Escherichia coli
dUTPase
-
Saccharomyces cerevisiae
dUTPase
-
Trypanosoma cruzi
dUTPase
-
Leishmania major
dUTPase
-
Campylobacter jejuni
dUTPase
-
Mycobacterium tuberculosis
More the enzyme belongs to the Nudix superfamily of enzymes Staphylococcus aureus
More the enzyme belongs to the Nudix superfamily of enzymes Escherichia coli
More the enzyme belongs to the Nudix superfamily of enzymes Saccharomyces cerevisiae
More the enzyme belongs to the Nudix superfamily of enzymes Trypanosoma cruzi
More the enzyme belongs to the Nudix superfamily of enzymes Leishmania major
More the enzyme belongs to the Nudix superfamily of enzymes Campylobacter jejuni
More the enzyme belongs to the Nudix superfamily of enzymes Mycobacterium tuberculosis