Inhibitors | Comment | Organism | Structure |
---|---|---|---|
adenosine 5'-tetraphosphate | Ki in nanomolar range | Rattus norvegicus | |
guanosine 5'-tetraphosphate | Ki in nanomolar range | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
P1,P4-bis(5'-adenosyl) tetraphosphate | - |
Rattus norvegicus | |
0.002 | - |
P1,P4-bis(5'-guanosyl) tetraphosphate | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required, maximum activity at 5 mM | Rattus norvegicus | |
Mn2+ | 15% of maximum activity | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
22000 | - |
gel filtration | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O | Rattus norvegicus | - |
ATP + AMP | - |
? | |
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O | Rattus norvegicus | - |
GTP + GMP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Rattus norvegicus |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.002 | - |
crude extract | Rattus norvegicus |
0.436 | - |
partially purified enzyme | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
P1,P4-bis(5'-adenosyl) tetraphosphate + H2O | - |
Rattus norvegicus | ATP + AMP | - |
? | |
P1,P4-bis(5'-guanosyl)tetraphosphate + H2O | - |
Rattus norvegicus | GTP + GMP | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Rattus norvegicus |