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Literature summary for 3.6.1.13 extracted from
- Rat liver ADP-ribose pyrophosphatase-I as an in vitro target of the acetaminophen metabolite N-acetyl-p-benzoquinoneimine (1997), Biochim. Biophys. Acta, 1336, 403-4o8.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| N-acetyl-p-benzoquinoneimine | decreases Vmax to 30% of control values and increases the Km for ADPribose 2-3fold | Rattus norvegicus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | effect of N-acetyl-p-benzoquinoneimine on Km | Rattus norvegicus | |
| 0.00055 | - |
ADPribose | - |
Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADPribose + H2O | - |
Rattus norvegicus | AMP + D-ribose 5-phosphate | - |
? | |
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