Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | Q9ZN70 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
PPX | - |
Pseudomonas aeruginosa |
Organism | Comment | Expression |
---|---|---|
Pseudomonas aeruginosa | under nitrogen-limiting conditions, exopolyphosphatase expression is controlled from a sigma54-dependent promoter activated by the response regulator NtrC. Under phosphate limitation, the expression is controlled from a sigma70 promoter, activated by PhoB | additional information |
General Information | Comment | Organism |
---|---|---|
physiological function | exopolyphosphatase Ppx is involved in the production of virulence factors associated with both acute infection (e.g. motility-promoting factors, blue/green pigment production, C6-C12 quorum-sensing homoserine lactones) and chronic infection (e.g. rhamnolipids, biofilm formation). Pseudomonas aeruginosa maintains consistently proper levels of Ppx regardless of environmental conditions. A mutant strain lacking Ppx activity does not grow in phosphate-deficient medium and the survival after 8 or 24 h declines by 25-30% of the initial value | Pseudomonas aeruginosa |