Activating Compound | Comment | Organism | Structure |
---|---|---|---|
N-acetylgalactosamine | - |
Homo sapiens | |
N-acetylglucosamine | - |
Homo sapiens | |
UDP-N-acetylglucosamine | slight activation at 0.00167-0.167 mM, slight inhibition at 1.67 mM | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | - |
Homo sapiens | |
D-fructose 1,6-diphosphate | - |
Homo sapiens | |
D-fructose 6-phosphate | - |
Homo sapiens | |
D-glucose 6-phosphate | - |
Homo sapiens | |
EDTA | no inhibition | Homo sapiens | |
N-acetylglucosamine 6-phosphate | - |
Homo sapiens | |
Ni2+ | - |
Homo sapiens | |
UDP-N-acetylglucosamine | slight inhibition at 1.67 mM, slight activation at 0.00167-0.167 mM | Homo sapiens | |
Zn2+ | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.041 | - |
D-glucosamine 6-phosphate | pH 9, 37°C | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the activity of the enzyme in erythrocytes is low, indicating that hexosamine catabolism is not a major source of energy in the erythrocyte | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucosamine 6-phosphate + H2O | - |
Homo sapiens | D-fructose 6-phosphate + NH3 | - |
? | |
additional information | the activity of the enzyme in erythrocytes is low, indicating that hexosamine catabolism is not a major source of energy in the erythrocyte | Homo sapiens | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Homo sapiens |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
32 | 47 | about 90% of maximal activity at 32°C and 47°C | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9 | - |
- |
Homo sapiens |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Homo sapiens | chromatofocusing | - |
8.55 |