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Literature summary for 3.5.5.5 extracted from
- Exploring the potential of fungal arylacetonitrilases in mandelic acid synthesis (2015), Mol. Biotechnol., 57, 466-474 .
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | the enzyme is promising for the enantioretentive transformation of (S)-mandelonitrile | Aspergillus niger |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression ion Escherichia coli | Aspergillus niger |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aspergillus niger | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (S)-mandelonitrile + 2 H2O | the enzyme produces up to more than 70 g/l of (R)-mandelic acid (enantiomeric excess 94.5-95.6%) in batch or fed-batch mode. Its volumetric productivities are the highest in batch mode (571 g/l*d) and its catalyst productivities in fed-batch mode (39.9 g/g of dcw) | Aspergillus niger | (R)-mandelic acid + NH3 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NitAn | - |
Aspergillus niger |
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Release 2023.1 (January 2023)
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