Literature summary for 3.5.4.6 extracted from

Dutka, P.; Szydlowska, M.; Chodorowski, Z.; Rybakowska, I.; Nagel-Starczynowska, G.; Kaletha, K.
AMP-deaminase from normal and cirrhotic human liver: a comparative study (2004), Mol. Cell. Biochem., 262, 119-126.

Search for more literature for 3.5.4.6

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	normal and cirrhotic	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5'-AMP + H2O	-	Homo sapiens	IMP + NH3	-	?

Subunits

Subunits	Comment	Organism
More	in contrast to AMP-deaminase isolated from the normal, healthy liver, where presence of relatively large (68 kDa) protein fragment is also detected, only smaller protein fragments are identified, while SDS-PAGE of AMP-deaminase isolated from the cirrhotic liver is performed	Homo sapiens

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
6	-	enzyme from cirrhotic liver	Homo sapiens
6.6	-	enzyme from normal liver	Homo sapiens

pH Range

pH Minimum	pH Maximum	Comment	Organism
6	7.2	pH 6.0: about 55% of maximal activity, pH 7.2: about 55% of maximal activity, normal liver	Homo sapiens

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Release 2023.1 (January 2023)