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Literature summary for 3.5.4.5 extracted from

  • Dang, Y.; Abudu, A.; Son, S.; Harjes, E.; Spearman, P.; Matsuo, H.; Zheng, Y.H.
    Identification of a single amino acid required for APOBEC3 antiretroviral cytidine deaminase activity (2011), J. Virol., 85, 5691-5695.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining

General Information

General Information Comment Organism
additional information sequence comparison of A3 proteins that have two cytidine deaminase, CDA, motifs, overview Homo sapiens
physiological function A3DE exhibits relatively low levels of anti-human immunodeficiency virus type 1, anti-HIV-1, activity, Vif still neutralizes this activity. The A3DE region II is responsible for the low activity of A3DE Homo sapiens