Protein Variants | Comment | Organism |
---|---|---|
F137W/W113F | 5-fluorozebularine does not protect mutant enzyme from dissociation by SDS as it does protect the wild-type enzyme | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-fluorozebularine | - |
Homo sapiens | |
SDS | wild-type tetramer dissociates into enzymatically inactive monomers, without intermediate forms via a non-cooperative transition. Extensive dialysis or dilution of the inativated monomers restores completely the activity. 5-Fluorozebularine disfavours dissociation of the tetramer into subunits in the wild-type enzyme, but not in the mutant enzyme F137W/W113F | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Subunits | Comment | Organism |
---|---|---|
More | wild-type tetramer dissociates into enzymatically inactive monomers, without intermediate forms via a non-cooperative transition. Extensive dialysis or dilution of the inativated mponomers restores completely the activity | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
CDA | - |
Homo sapiens |