BRENDA - Enzyme Database show
show all sequences of 3.5.4.5

Purification and properties of Escherichia coli cytidine deaminase by amplification of the cdd gene

Kwon, T.K.; Lee, S.Y.; Kim, J.G.; Song, B.H.; Hong, S.D.; Mol. Cells 1, 281-286 (1991)
No PubMed abstract available

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
cdd gene cloned and amplified with pTK148, cloning vector pBR322, enzyme overexpression in Escherichia coli C600
Escherichia coli
cdd genes cloned and characterized
Bacillus subtilis
cdd genes cloned and characterized
Salmonella enterica subsp. enterica serovar Typhimurium
Inhibitors
Inhibitors
Commentary
Organism
Structure
3,4,5,6-Tetrahydrouridine
-
Escherichia coli
5,6-Dihydrouridine
competitive inhibition
Escherichia coli
5-bromodeoxyuridine
-
Escherichia coli
adenosine
-
Escherichia coli
Cu2+
-
Escherichia coli
deoxyadenosine
competitive inhibition
Escherichia coli
deoxyguanosine
-
Escherichia coli
deoxyuridine
competitive inhibition
Escherichia coli
Fe2+
-
Escherichia coli
Fe3+
-
Escherichia coli
guanosine
-
Escherichia coli
Hg+
-
Escherichia coli
p-chloromercuribenzoate
-
Saccharomyces cerevisiae
thioglycolic acid
0.7 mM 88% relative activity, complete inhibition at 7 mM
Escherichia coli
thymidine
competitive inhibition
Escherichia coli
uridine
-
Escherichia coli
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0167
-
cytidine
nonhomogenous enzyme
Escherichia coli
0.089
-
cytosine deoxyriboside
-
Escherichia coli
0.21
-
deoxycytidine
amplified gene
Escherichia coli
0.58
-
deoxycytidine
-
Escherichia coli
2.2
-
cytidine
homogenous preparation
Escherichia coli
6.6
-
cytidine
amplified gene, pH 7.0, 37°C
Escherichia coli
8.53
-
deoxycytidine
-
Escherichia coli
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
inner-surface of cytoplasmic membrane
Escherichia coli
5737
-
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
14000
-
4 * 14000, deduced from cdd structural gene nucleotide sequence and mini-cell experiments
Bacillus subtilis
33000
-
2 * 33000, SDS-PAGE
Escherichia coli
34000
-
2 * 34000, SDS-PAGE
Escherichia coli
54000
-
-
Escherichia coli
56000
-
calculated from Stokes radius
Bacillus subtilis
56000
-
calculated from Stokes radius
Escherichia coli
57000
-
gel filtration, homogenous preparation
Escherichia coli
62000
-
gel filtration, native enzyme
Escherichia coli
73000
-
gel filtration, nonhomogenous preparation
Escherichia coli
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
cytidine + H2O
Salmonella enterica subsp. enterica serovar Typhimurium
-
uridine + NH3
-
-
?
cytidine + H2O
Bacillus subtilis
-
uridine + NH3
-
-
?
cytidine + H2O
Escherichia coli
-
uridine + NH3
-
-
?
cytidine + H2O
Saccharomyces cerevisiae
-
uridine + NH3
-
-
?
cytidine + H2O
Geobacillus stearothermophilus
-
uridine + NH3
-
-
?
cytidine + H2O
Escherichia coli JF611
-
uridine + NH3
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Bacillus subtilis
-
-
-
Escherichia coli
-
-
-
Escherichia coli JF611
-
-
-
Geobacillus stearothermophilus
-
-
-
Saccharomyces cerevisiae
-
bakers' yeast
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
Purification (Commentary)
Commentary
Organism
-
Escherichia coli
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
4
-
amplified gene, 5'-aza-2'-deoxycytidine as substrate
Escherichia coli
4.9
-
amplified gene, 2'-thiocytidine as substrate
Escherichia coli
23.9
-
amplified gene, 5'-methylcytidine as substrate
Escherichia coli
31.8
-
amplified gene, ara-cytidine as substrate
Escherichia coli
43
-
amplified gene, cytidine as substrate
Escherichia coli
47.9
-
amplified gene, 5'-methyl-2'-deoxycytidine as substrate
Escherichia coli
68.4
-
amplified gene, 2'-fluoro-2'-deoxycytidine as substrate
Escherichia coli
97.6
-
amplified gene, deoxycytidine as substrate
Escherichia coli
3558
-
amplified gene
Escherichia coli
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1-beta-D-arabinofuranosylcytosine + H2O
-
209660
Escherichia coli
?
-
-
-
?
2'-deoxycytidine + H2O
-
209660
Escherichia coli
2'-deoxyuridine + NH3
-
-
-
?
2'-deoxycytidine + H2O
-
209660
Saccharomyces cerevisiae
2'-deoxyuridine + NH3
-
-
-
?
2'-deoxycytidine + H2O
-
209660
Escherichia coli JF611
2'-deoxyuridine + NH3
-
-
-
?
2'-fluoro-2'-deoxycytidine + H2O
-
209660
Escherichia coli
2'-fluoro-2'-deoxyuridine + NH3
-
-
-
?
2'-fluoro-2'-deoxycytidine + H2O
-
209660
Escherichia coli JF611
2'-fluoro-2'-deoxyuridine + NH3
-
-
-
?
2'-thio-cytidine + H2O
-
209660
Escherichia coli
2'-thiouridine + NH3
-
-
-
?
5'-methyl-2'-deoxycytidine + H2O
-
209660
Escherichia coli
5'-methyl-2-deoxyuridine + NH3
-
-
-
?
5'-methyl-2'-deoxycytidine + H2O
-
209660
Escherichia coli JF611
5'-methyl-2-deoxyuridine + NH3
-
-
-
?
5-aza-2'-deoxycytidine + H2O
-
209660
Escherichia coli
5-aza-2'-deoxyuridine + NH3
-
-
-
?
5-methylcytidine + H2O
-
209660
Escherichia coli
5-methyluridine + NH3
-
-
-
?
5-methylcytidine + H2O
-
209660
Escherichia coli JF611
5-methyluridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Salmonella enterica subsp. enterica serovar Typhimurium
uridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Bacillus subtilis
uridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Escherichia coli
uridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Saccharomyces cerevisiae
uridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Geobacillus stearothermophilus
uridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Escherichia coli JF611
uridine + NH3
-
-
-
?
Subunits
Subunits
Commentary
Organism
dimer
2 * 33000, SDS-PAGE; 2 * 34000, SDS-PAGE
Escherichia coli
tetramer
4 * 14000, deduced from cdd structural gene nucleotide sequence and mini-cell experiments
Bacillus subtilis
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
-
Escherichia coli
30
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
60
-
relatively labile to thermal treatment, complete inactivation by incubation for 30 min
Escherichia coli
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
-
Escherichia coli
7
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
6
9
reasonably stable in this range
Escherichia coli
Cloned(Commentary) (protein specific)
Commentary
Organism
cdd genes cloned and characterized
Bacillus subtilis
cdd gene cloned and amplified with pTK148, cloning vector pBR322, enzyme overexpression in Escherichia coli C600
Escherichia coli
cdd genes cloned and characterized
Salmonella enterica subsp. enterica serovar Typhimurium
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
3,4,5,6-Tetrahydrouridine
-
Escherichia coli
5,6-Dihydrouridine
competitive inhibition
Escherichia coli
5-bromodeoxyuridine
-
Escherichia coli
adenosine
-
Escherichia coli
Cu2+
-
Escherichia coli
deoxyadenosine
competitive inhibition
Escherichia coli
deoxyguanosine
-
Escherichia coli
deoxyuridine
competitive inhibition
Escherichia coli
Fe2+
-
Escherichia coli
Fe3+
-
Escherichia coli
guanosine
-
Escherichia coli
Hg+
-
Escherichia coli
p-chloromercuribenzoate
-
Saccharomyces cerevisiae
thioglycolic acid
0.7 mM 88% relative activity, complete inhibition at 7 mM
Escherichia coli
thymidine
competitive inhibition
Escherichia coli
uridine
-
Escherichia coli
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0167
-
cytidine
nonhomogenous enzyme
Escherichia coli
0.089
-
cytosine deoxyriboside
-
Escherichia coli
0.21
-
deoxycytidine
amplified gene
Escherichia coli
0.58
-
deoxycytidine
-
Escherichia coli
2.2
-
cytidine
homogenous preparation
Escherichia coli
6.6
-
cytidine
amplified gene, pH 7.0, 37°C
Escherichia coli
8.53
-
deoxycytidine
-
Escherichia coli
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
inner-surface of cytoplasmic membrane
Escherichia coli
5737
-
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
14000
-
4 * 14000, deduced from cdd structural gene nucleotide sequence and mini-cell experiments
Bacillus subtilis
33000
-
2 * 33000, SDS-PAGE
Escherichia coli
34000
-
2 * 34000, SDS-PAGE
Escherichia coli
54000
-
-
Escherichia coli
56000
-
calculated from Stokes radius
Bacillus subtilis
56000
-
calculated from Stokes radius
Escherichia coli
57000
-
gel filtration, homogenous preparation
Escherichia coli
62000
-
gel filtration, native enzyme
Escherichia coli
73000
-
gel filtration, nonhomogenous preparation
Escherichia coli
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
cytidine + H2O
Salmonella enterica subsp. enterica serovar Typhimurium
-
uridine + NH3
-
-
?
cytidine + H2O
Bacillus subtilis
-
uridine + NH3
-
-
?
cytidine + H2O
Escherichia coli
-
uridine + NH3
-
-
?
cytidine + H2O
Saccharomyces cerevisiae
-
uridine + NH3
-
-
?
cytidine + H2O
Geobacillus stearothermophilus
-
uridine + NH3
-
-
?
cytidine + H2O
Escherichia coli JF611
-
uridine + NH3
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Escherichia coli
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
4
-
amplified gene, 5'-aza-2'-deoxycytidine as substrate
Escherichia coli
4.9
-
amplified gene, 2'-thiocytidine as substrate
Escherichia coli
23.9
-
amplified gene, 5'-methylcytidine as substrate
Escherichia coli
31.8
-
amplified gene, ara-cytidine as substrate
Escherichia coli
43
-
amplified gene, cytidine as substrate
Escherichia coli
47.9
-
amplified gene, 5'-methyl-2'-deoxycytidine as substrate
Escherichia coli
68.4
-
amplified gene, 2'-fluoro-2'-deoxycytidine as substrate
Escherichia coli
97.6
-
amplified gene, deoxycytidine as substrate
Escherichia coli
3558
-
amplified gene
Escherichia coli
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1-beta-D-arabinofuranosylcytosine + H2O
-
209660
Escherichia coli
?
-
-
-
?
2'-deoxycytidine + H2O
-
209660
Escherichia coli
2'-deoxyuridine + NH3
-
-
-
?
2'-deoxycytidine + H2O
-
209660
Saccharomyces cerevisiae
2'-deoxyuridine + NH3
-
-
-
?
2'-deoxycytidine + H2O
-
209660
Escherichia coli JF611
2'-deoxyuridine + NH3
-
-
-
?
2'-fluoro-2'-deoxycytidine + H2O
-
209660
Escherichia coli
2'-fluoro-2'-deoxyuridine + NH3
-
-
-
?
2'-fluoro-2'-deoxycytidine + H2O
-
209660
Escherichia coli JF611
2'-fluoro-2'-deoxyuridine + NH3
-
-
-
?
2'-thio-cytidine + H2O
-
209660
Escherichia coli
2'-thiouridine + NH3
-
-
-
?
5'-methyl-2'-deoxycytidine + H2O
-
209660
Escherichia coli
5'-methyl-2-deoxyuridine + NH3
-
-
-
?
5'-methyl-2'-deoxycytidine + H2O
-
209660
Escherichia coli JF611
5'-methyl-2-deoxyuridine + NH3
-
-
-
?
5-aza-2'-deoxycytidine + H2O
-
209660
Escherichia coli
5-aza-2'-deoxyuridine + NH3
-
-
-
?
5-methylcytidine + H2O
-
209660
Escherichia coli
5-methyluridine + NH3
-
-
-
?
5-methylcytidine + H2O
-
209660
Escherichia coli JF611
5-methyluridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Salmonella enterica subsp. enterica serovar Typhimurium
uridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Bacillus subtilis
uridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Escherichia coli
uridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Saccharomyces cerevisiae
uridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Geobacillus stearothermophilus
uridine + NH3
-
-
-
?
cytidine + H2O
-
209660
Escherichia coli JF611
uridine + NH3
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
dimer
2 * 33000, SDS-PAGE; 2 * 34000, SDS-PAGE
Escherichia coli
tetramer
4 * 14000, deduced from cdd structural gene nucleotide sequence and mini-cell experiments
Bacillus subtilis
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
-
Escherichia coli
30
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
60
-
relatively labile to thermal treatment, complete inactivation by incubation for 30 min
Escherichia coli
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
-
Escherichia coli
7
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
6
9
reasonably stable in this range
Escherichia coli
Other publictions for EC 3.5.4.5
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
734018
Shibu
Characterization of a novel re ...
Brassica oleracea
J. Agric. Food Chem.
62
1796-1801
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-
-
1
-
-
-
-
2
-
-
1
3
-
6
-
-
1
-
-
-
-
-
3
1
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
1
3
-
-
-
1
-
-
-
-
3
1
1
-
-
-
1
-
-
-
-
1
1
-
-
-
718695
Sanchez-Quitian
Crystal structure determinatio ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Arch. Biochem. Biophys.
509
108-115
2011
-
1
-
1
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
2
2
-
-
-
712889
Sanchez-Quitian
Structural and functional anal ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
J. Struct. Biol.
169
413-423
2010
-
-
1
1
-
-
-
2
-
1
4
-
-
5
-
-
1
-
-
-
4
-
2
1
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
2
-
1
4
-
-
-
-
1
-
-
4
-
2
1
-
-
-
2
-
-
-
-
-
1
1
-
-
-
685915
Lemaire
Inhibition of cytidine deamina ...
Homo sapiens
Cancer Chemother. Pharmacol.
63
411-416
2009
-
-
1
-
-
-
1
1
-
-
-
2
-
4
-
-
1
-
-
-
-
-
4
-
1
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
2
-
-
-
1
-
-
-
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
695606
Sigmond
Gemcitabine uptake in glioblas ...
Homo sapiens
Ann. Oncol.
20
182-187
2009
-
1
-
-
-
-
-
2
-
-
-
1
-
2
-
-
-
-
-
2
1
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
-
-
-
2
1
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
711824
Wu
Identification and functional ...
Haliotis diversicolor supertexta
Dev. Comp. Immunol.
33
709-717
2009
-
-
1
-
-
-
-
-
2
1
2
1
-
3
-
-
1
-
-
5
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
2
1
2
1
-
-
-
1
-
5
-
-
1
1
-
-
-
-
-
-
-
1
1
1
1
1
-
-
712721
Park
Thermostability of chimeric cy ...
Bacillus caldolyticus, Bacillus caldolyticus DSM 405 (T53), Geobacillus stearothermophilus, Geobacillus stearothermophilus IFO12550 (T101)
J. Microbiol. Biotechnol.
19
1536-1541
2009
-
-
2
-
-
-
-
-
-
-
4
-
-
5
-
-
2
-
-
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-
4
2
-
-
2
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
2
-
-
-
-
4
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
699156
Besnard
Optimized blood sampling with ...
Homo sapiens
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
870
117-120
2008
-
-
-
-
-
-
1
-
-
-
-
1
-
2
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
700510
Giovannetti
Correlation between cytidine d ...
Homo sapiens
Nucleosides Nucleotides Nucleic Acids
27
720-725
2008
-
1
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
1
2
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
2
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
686066
Matsubara
-
The ONIOM molecular dynamics m ...
Homo sapiens
Chem. Phys. Lett.
437
138-142
2007
-
-
-
-
-
-
-
-
-
1
-
2
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689935
Vincenzetti
Modulation of human cytidine d ...
Homo sapiens
Proteins
70
144-156
2007
-
-
1
-
7
-
4
13
-
-
-
-
-
4
-
-
1
-
-
-
-
-
4
1
2
2
1
-
1
-
-
-
11
-
-
-
-
1
-
-
7
-
-
4
11
13
-
-
-
-
-
-
-
1
-
-
-
-
4
1
2
2
1
-
1
-
-
-
-
-
-
-
-
-
689995
Parise
Quantitative determination of ...
Mus musculus
Rapid Commun. Mass Spectrom.
21
1991-1997
2007
-
-
-
-
-
-
1
-
-
-
-
1
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
667736
Teh
The 1.48 A resolution crystal ...
Mus musculus
Biochemistry
45
7825-7833
2006
-
-
1
1
-
-
2
-
-
1
-
2
-
2
-
-
1
-
-
-
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
2
-
-
-
1
-
2
-
-
-
1
-
-
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
669610
Matsubara
A quantum chemical study of th ...
Escherichia coli
J. Chem. Inf. Model.
46
1276-1285
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
669910
Costanzi
Human cytidine deaminase: A th ...
Homo sapiens
J. Mol. Graph. Model.
25
10-16
2006
-
-
-
1
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
669137
Elshafei
Cytidine deaminase activity in ...
Penicillium palitans, Penicillium palitans NRC 510
J. Basic Microbiol.
45
335-343
2005
-
-
-
-
-
-
3
-
-
3
-
-
-
4
-
-
-
-
-
-
-
-
-
-
1
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
1
-
-
-
-
-
-
-
-
-
669792
Chung
Structure of human cytidine de ...
Homo sapiens
J. Med. Chem.
48
658-660
2005
-
-
-
1
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
654757
Johansson
Structural, kinetic, and mutat ...
Bacillus subtilis
Biochemistry
43
6020-6029
2004
-
-
1
1
5
-
-
6
-
1
-
-
-
1
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
5
-
-
-
-
6
-
1
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
670747
Vincenzetti
Isoenzymatic forms of human cy ...
Homo sapiens
Protein Eng. Des. Sel.
17
871-877
2004
-
-
-
-
-
-
6
11
-
-
2
-
-
2
-
-
-
-
-
2
-
-
5
1
-
-
-
-
-
-
-
-
10
3
-
-
-
-
-
-
-
-
-
6
10
11
-
-
2
-
-
-
-
-
-
2
-
-
5
1
-
-
-
-
-
-
-
3
-
-
-
-
-
-
657227
Vincenzetti
Functional properties of subun ...
Homo sapiens
Protein Eng.
16
1055-1061
2003
-
-
-
-
1
-
2
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
650635
Sakai
Isolation from Nocardioides sp ...
Nocardioides sp., Nocardioides sp. CT16
Biosci. Biotechnol. Biochem.
66
1646-1651
2002
-
-
-
-
-
-
-
3
-
-
2
-
-
4
-
-
1
-
-
-
1
-
6
1
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
2
-
-
-
-
1
-
-
1
-
6
1
1
-
2
-
-
-
-
-
-
-
-
-
-
-
654638
Johansson
Crystal structure of the tetra ...
Bacillus subtilis
Biochemistry
41
2563-2570
2002
-
-
-
1
-
-
-
-
-
1
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657220
Cambi
Cytidine deaminase from two ex ...
Bacillus caldolyticus, Bacillus subtilis, Sporosarcina psychrophila
Protein Eng.
14
807-813
2001
-
-
2
-
-
2
-
-
-
-
4
-
-
7
-
-
2
-
1
-
-
-
3
2
3
3
3
-
-
-
-
-
-
3
-
-
-
2
-
-
-
2
-
-
-
-
-
-
4
-
-
-
-
2
1
-
-
-
3
2
3
3
3
-
-
-
-
3
-
-
-
-
-
-
209667
Carlow
Cytidine deaminases from B. su ...
Bacillus subtilis, Escherichia coli, Escherichia coli SO268, Homo sapiens
Biochemistry
38
12258-12265
1999
-
-
1
-
-
-
11
-
-
-
2
4
-
6
-
-
-
-
-
-
2
-
4
2
-
-
-
-
-
2
-
-
-
-
-
-
-
1
-
-
-
-
-
11
-
-
-
-
2
4
-
-
-
-
-
-
2
-
4
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
209668
Vincenzetti
Cloning, expression, and purif ...
Arabidopsis thaliana, Bacillus subtilis, Escherichia coli, Escherichia coli SO5201, Gallus gallus, Haemophilus influenzae, Mus musculus, Mus musculus BALB/c, Ovis aries
Protein Expr. Purif.
15
8-15
1999
-
-
1
1
-
-
15
10
-
-
6
9
-
68
-
-
1
-
-
-
1
-
26
4
-
-
-
-
-
1
1
-
-
-
-
-
-
1
-
1
-
-
-
15
-
10
-
-
6
9
-
-
-
1
-
-
1
-
26
4
-
-
-
-
-
1
1
-
-
-
-
-
-
-
209669
Faivre-Nitschke
A prokaryotic-type cytidine de ...
Arabidopsis thaliana, Bacillus subtilis, Brugia pahangi, Caenorhabditis elegans, Escherichia coli, Escherichia coli BL21(D3), Haemophilus influenzae, Homo sapiens, Mycoplasma pneumoniae, Saccharomyces cerevisiae
Eur. J. Biochem.
263
896-903
1999
-
1
1
-
-
-
11
6
2
-
2
10
-
15
-
-
-
-
-
-
-
1
24
3
-
-
-
-
1
1
-
-
-
-
-
-
1
1
-
-
-
-
-
11
-
6
2
-
2
10
-
-
-
-
-
-
-
1
24
3
-
-
-
-
1
1
-
-
-
-
-
-
-
-
209534
Kroep
Role of deoxycytidine kinase ( ...
Homo sapiens
Adv. Exp. Med. Biol.
431
657-660
1998
-
1
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209531
Jahns-Streubel
-
Correlation of deoxycytidine d ...
Homo sapiens
Haematol. Blood Transfus.
38
252-259
1997
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209666
Vincenzetti
Human placenta cytidine deamin ...
Bacillus subtilis, Homo sapiens
Biochemistry
42
469-476
1997
-
-
1
-
-
-
2
-
-
-
-
2
-
3
-
-
1
-
-
7
-
-
3
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
2
-
-
-
1
-
7
-
-
3
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209665
Vincenzetti
Recombinant human cytidine dea ...
Bacillus subtilis, Escherichia coli, Escherichia coli DH5-alpha, Homo sapiens
Protein Expr. Purif.
8
247-253
1996
-
-
1
1
-
-
9
6
-
-
6
4
-
19
-
-
1
-
-
8
1
1
13
3
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
1
-
-
-
9
-
6
-
-
6
4
-
-
-
1
-
8
1
1
13
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
209642
Betts
Cytidine deaminase.The 2.3 A c ...
Escherichia coli
J. Mol. Biol.
235
635-656
1994
-
-
-
1
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209664
Smith
Mutations affecting transition ...
Escherichia coli
Biochemistry
33
6468-6474
1994
-
-
1
-
-
-
2
5
-
1
1
1
-
2
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
5
-
1
1
1
-
-
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209533
Ruiz van Haperen
Deoxycytidine kinase and deoxy ...
Homo sapiens
Eur. J. Cancer
29A
2132-2137
1993
-
1
-
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
9
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
9
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209663
Bouffard
Kinetic studies on 2',2'-diflu ...
Homo sapiens
Biochem. Pharmacol.
45
1857-1861
1993
-
1
-
-
-
-
2
2
-
-
-
1
-
2
-
-
1
-
-
3
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
2
-
-
-
1
-
-
-
1
-
3
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209532
Mancini
The role of deoxycytidine-meta ...
Homo sapiens
Cancer Chemother. Pharmacol.
30
139-144
1992
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209662
Barchi
-
Inhibition of cytidine deamina ...
Homo sapiens, Mus musculus, Mus musculus BALB/c
Nucleosides Nucleotides
11
1781-1793
1992
-
1
-
-
-
-
4
1
-
-
-
3
-
58
-
-
-
-
-
6
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
4
-
1
-
-
-
3
-
-
-
-
-
6
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209660
Kwon
-
Purification and properties of ...
Bacillus subtilis, Escherichia coli, Escherichia coli JF611, Geobacillus stearothermophilus, Saccharomyces cerevisiae, Salmonella enterica subsp. enterica serovar Typhimurium
Mol. Cells
1
281-286
1991
-
-
3
-
-
-
16
7
1
-
9
6
-
6
-
-
1
-
-
-
9
-
18
2
2
-
1
-
2
-
1
-
-
-
-
-
-
3
-
-
-
-
-
16
-
7
1
-
9
6
-
-
-
1
-
-
9
-
18
2
2
-
1
-
2
-
1
-
-
-
-
-
-
-
209661
Cacciamani
Purification of human cytidine ...
Canis lupus familiaris, Escherichia coli, Gallus gallus, Homo sapiens, Mus musculus, Mus musculus BALB/c, no activity in Lactobacillus sp., no activity in Moraxella sp., no activity in Pseudomonas sp.
Arch. Biochem. Biophys.
290
285-292
1991
-
1
-
-
-
-
45
-
-
-
2
6
-
65
-
-
2
-
-
11
1
1
41
2
-
-
-
-
1
1
1
-
-
-
-
-
1
-
-
-
-
-
-
45
-
-
-
-
2
6
-
-
-
2
-
11
1
1
41
2
-
-
-
-
1
1
1
-
-
-
-
-
-
-
209657
Fanucchi
Kinetics and substrate specifi ...
Canis lupus familiaris, Homo sapiens
Biochem. Pharmacol.
35
1199-1201
1986
-
-
-
-
-
-
1
9
-
-
-
2
-
4
-
-
-
-
-
2
-
-
10
-
-
-
-
-
-
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-
-
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-
-
-
-
-
-
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1
-
9
-
-
-
2
-
-
-
-
-
2
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209658
Vita
-
Further properties of cytidine ...
Escherichia coli, Escherichia coli B / ATCC 11303
Ital. J. Biochem.
35
145A-147A
1986
-
-
-
-
-
-
6
2
-
-
2
2
-
177
-
-
1
-
-
-
-
-
6
1
-
-
-
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
6
-
2
-
-
2
2
-
-
-
1
-
-
-
-
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209659
Nygaard
On the role of cytidine deamin ...
Escherichia coli, Homo sapiens, Mus musculus, Mus musculus BALB/c, no activity in Lactobacillus sp., no activity in Moraxella sp., no activity in Pseudomonas sp., Ovis aries, Saccharomyces cerevisiae, Salmonella enterica subsp. enterica serovar Typhimurium, Zea mays
Adv. Exp. Med. Biol.
195B
415-420
1986
3
1
-
-
-
-
-
-
-
-
-
8
-
66
-
-
2
-
-
11
-
-
25
-
-
-
-
-
-
-
-
-
-
-
-
3
1
-
-
-
-
-
-
-
-
-
-
-
-
8
-
-
-
2
-
11
-
-
25
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209655
Vita
Cytidine deaminase from Escher ...
Escherichia coli, Escherichia coli B / ATCC 11303
Biochemistry
24
6020-6024
1985
-
-
-
-
-
-
9
3
-
-
3
2
-
179
-
-
1
-
-
-
-
4
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
9
-
3
-
-
3
2
-
-
-
1
-
-
-
4
6
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209656
Holy
-
Preparation of analogues of cy ...
Escherichia coli, Escherichia coli A19, Macaca mulatta, Mus musculus, Mus musculus BALB/c, Saccharomyces cerevisiae
Collect. Czech. Chem. Commun.
50
393-417
1985
-
-
-
-
-
1
5
-
-
-
-
6
-
63
-
-
1
-
-
3
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
5
-
-
-
-
-
6
-
-
-
1
-
3
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209652
Kidder
Characteristics of cytidine am ...
Crithidia fasciculata, Trypanosoma cruzi
J. Protozool.
31
298-300
1984
6
-
-
-
-
2
2
4
-
-
2
2
-
5
-
-
-
-
-
-
-
4
4
-
-
-
-
-
2
-
-
-
-
-
-
6
-
-
-
-
-
2
-
2
-
4
-
-
2
2
-
-
-
-
-
-
-
4
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
209653
Ashley
Purification and properties of ...
Escherichia coli, Escherichia coli B / ATCC 11303, Homo sapiens, Mus musculus, Mus musculus BALB/c, Ovis aries, Saccharomyces cerevisiae, Zea mays
J. Biol. Chem.
259
13615-13620
1984
-
-
-
-
-
-
9
3
-
-
5
8
-
239
-
-
5
-
-
5
1
2
26
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
9
-
3
-
-
5
8
-
-
-
5
-
5
1
2
26
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209654
Ashley
Inhibition of Escherichia coli ...
Escherichia coli, Homo sapiens
J. Biol. Chem.
259
13621-13627
1984
-
-
-
-
-
-
3
-
-
-
1
2
-
3
-
-
-
-
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
1
2
-
-
-
-
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209528
Chan
Differences in deoxycytidine m ...
Mus musculus
Biochem. J.
210
367-371
1983
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209650
Ashley
A phosphorus-containing pyrimi ...
Escherichia coli, Escherichia coli B / ATCC 11303
Biochem. Biophys. Res. Commun.
108
1467-1474
1982
-
-
-
-
-
-
1
2
-
-
-
2
-
177
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209651
Kara
-
Sensitivity of some arabinosyl ...
Mus musculus, Mus musculus BALB/c
Collect. Czech. Chem. Commun.
47
2824-2830
1982
-
-
-
-
-
-
2
-
-
-
-
2
-
57
-
-
-
-
-
1
-
1
13
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
1
-
1
13
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209492
Ipata
Cytosine and cytidine deaminas ...
Escherichia coli, Mus musculus, Mus musculus BALB/c, Saccharomyces cerevisiae
Methods Enzymol.
51
394-401
1978
-
-
-
-
-
-
11
3
-
-
1
4
-
60
-
-
1
-
-
1
1
2
8
-
-
1
-
-
2
-
1
-
2
-
-
-
-
-
-
-
-
-
-
11
2
3
-
-
1
4
-
-
-
1
-
1
1
2
8
-
-
1
-
-
2
-
1
-
-
-
-
-
-
-
209527
Cullen
Bromodeoxyuridine induction of ...
Cricetinae, Mus musculus
Biochim. Biophys. Acta
517
158-168
1978
1
-
-
-
-
-
-
-
-
-
-
2
-
3
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209648
Wentworth
Cytidine deaminases (from Esch ...
Canis lupus familiaris, Cavia porcellus, Columba sp., Escherichia coli, Escherichia coli B / ATCC 11303, Felis catus domesticus, Homo sapiens, Macaca mulatta, Mus musculus, Mus musculus BALB/c, Oryctolagus cuniculus, Rana sp., Rattus norvegicus, Sus scrofa
Methods Enzymol.
51
401-407
1978
-
-
-
-
-
-
4
7
-
-
1
14
-
244
-
-
2
-
-
15
1
1
40
-
-
-
-
-
3
1
1
-
-
-
-
-
-
-
-
-
-
-
-
4
-
7
-
-
1
14
-
-
-
2
-
15
1
1
40
-
-
-
-
-
3
1
1
-
-
-
-
-
-
-
209649
Rothman
Cytidine deaminase from leukem ...
Homo sapiens, Mus musculus, Mus musculus BALB/c
Methods Enzymol.
51
408-412
1978
3
1
-
-
-
-
7
3
-
1
1
3
-
59
-
-
1
-
-
9
1
2
21
-
-
-
1
-
2
-
-
-
-
-
-
3
1
-
-
-
-
-
-
7
-
3
-
1
1
3
-
-
-
1
-
9
1
2
21
-
-
-
1
-
2
-
-
-
-
-
-
-
-
-
209645
Wentworth
On the interaction of 3,4,5,6- ...
Escherichia coli, Homo sapiens
Biochemistry
14
5099-5105
1975
-
1
-
-
-
-
2
3
-
-
-
2
-
3
-
-
-
-
-
3
-
-
8
-
-
-
-
-
3
-
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
3
-
-
-
2
-
-
-
-
-
3
-
-
8
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
209646
Evans
The action of bacterial cytidi ...
Escherichia coli
Biochemistry
14
621-624
1975
-
-
-
-
-
-
1
2
-
-
-
1
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209526
Le Floc`h
-
La desoxycytidine aminohydrola ...
Zea mays
Phytochemistry
13
2503-2509
1974
-
-
-
-
-
-
6
-
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209529
Kang
-
Metabolism of pyrimidine deoxy ...
Mus musculus
Korean J. Zool.
17
107-116
1974
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209643
Abell
Cytidine deaminase in human ly ...
Homo sapiens
Nature New Biol.
244
217-219
1973
-
1
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209644
Hosono
The purification and propertie ...
Bacillus cereus, Escherichia coli, Escherichia coli Y-70-272, Mus musculus, Mus musculus BALB/c, Ovis aries, Saccharomyces cerevisiae
J. Biochem.
74
797-803
1973
5
-
-
-
-
-
26
5
-
4
1
7
-
63
-
-
1
-
-
2
1
-
22
1
-
-
-
-
1
-
-
-
-
-
-
5
-
-
-
-
-
-
-
26
-
5
-
4
1
7
-
-
-
1
-
2
1
-
22
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
209530
Taketo
Internal localization of nucle ...
Escherichia coli
J. Biochem.
72
1557-1563
1972
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
209641
Cohen
Cytidine deaminase from Escher ...
Escherichia coli, Escherichia coli B / ATCC 11303, Homo sapiens, Mus musculus, Mus musculus BALB/c, Ovis aries, Saccharomyces cerevisiae
J. Biol. Chem.
246
7561-7565
1971
-
-
-
-
-
-
7
4
-
-
1
7
-
238
-
-
1
-
-
5
-
1
9
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
7
-
4
-
-
1
7
-
-
-
1
-
5
-
1
9
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
209639
Wang
Enzymatic deamination of cytos ...
Bos taurus, Escherichia coli, Escherichia coli 15 (ATCC 9723), Mus musculus, Mus musculus BALB/c, Oryctolagus cuniculus, Saccharomyces cerevisiae
J. Biol. Chem.
184
17-28
1950
-
-
-
-
-
-
1
2
-
-
-
7
-
62
-
-
-
-
-
4
-
1
7
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
7
-
-
-
-
-
4
-
1
7
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-