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Literature summary for 3.5.4.5 extracted from

  • Fanucchi, M.P.; Watanabe, K.A.; Fox, J.J.; Chou, T.
    Kinetics and substrate specificity of human and canine cytidine deaminase (1986), Biochem. Pharmacol., 35, 1199-1201.
    View publication on PubMed
Search for more literature for 3.5.4.5

Inhibitors

Inhibitors Comment Organism Structure
3,4,5,6-Tetrahydrouridine
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.049
-
 cytidine
-
 Homo sapiens
0.055
-
 deoxycytidine
-
 Homo sapiens
0.27
-
 1-beta-D-arabinofuranosylcytosine
-
 Homo sapiens
0.31
-
 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine leukemia enzyme Homo sapiens
0.33
-
 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)cytosine
-
 Homo sapiens
0.51
-
 1-beta-D-arabinofuranosylcytosine
-
 Canis lupus familiaris
0.66
-
 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)cytosine
-
 Canis lupus familiaris
2.8
-
 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine
-
 Homo sapiens
3.9
-
 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine
-
 Canis lupus familiaris

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cytidine + H2O Homo sapiens
-
 uridine + NH3
-
 ?
cytidine + H2O Canis lupus familiaris
-
 uridine + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris
-
 dog
-
Homo sapiens
-
 human
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-
liver
-
 Canis lupus familiaris
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine + H2O
-
 Homo sapiens ?
-
 ?
1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine + H2O FIAC poorly deminated Canis lupus familiaris ?
-
 ?
1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)cytosine + H2O
-
 Homo sapiens ?
-
 ?
1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)cytosine + H2O
-
 Canis lupus familiaris ?
-
 ?
1-beta-D-arabinofuranosylcytosine + H2O
-
 Homo sapiens ?
-
 ?
1-beta-D-arabinofuranosylcytosine + H2O
-
 Canis lupus familiaris ?
-
 ?
cytidine + H2O
-
 Homo sapiens uridine + NH3
-
 ?
cytidine + H2O
-
 Canis lupus familiaris uridine + NH3
-
 ?
deoxycytidine + H2O
-
 Homo sapiens deoxyuridine + NH3
-
 ?
deoxycytidine + H2O
-
 Canis lupus familiaris deoxyuridine + NH3
-
 ?

Synonyms

Synonyms Comment Organism
canine hepatic cyd deaminase
-
 Canis lupus familiaris
cyd deaminase
-
 Homo sapiens
cyd deaminase
-
 Canis lupus familiaris