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Literature summary for 3.5.4.4 extracted from

  • Bhattacharjee, P.; Sharma, R.
    Antithetical effects of corticosterone and dibutyryl cAMP on adenosine deaminase in the gastrointestinal tract of chicken during postnatal development (2009), Mol. Cell. Biochem., 327, 79-86.
    View publication on PubMed
Search for more literature for 3.5.4.4

Activating Compound

Activating Compound Comment Organism Structure
dibutyryl-cAMP causes a significant increase in the activity level of adenosine deaminase depending on the regions of the gastrointestinal tract Gallus gallus

Inhibitors

Inhibitors Comment Organism Structure
corticosterone inhibits the adenosine deaminase activity in an age- and region-specific manner Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2'-deoxyadenosine + H2O Gallus gallus
-
 2'-deoxyinosine + NH3
-
 ir
adenosine + H2O Gallus gallus
-
 inosine + NH3
-
 ir

Organism

Organism UniProt Comment Textmining
Gallus gallus Q5ZKP6 Babcock Venkateswara 380, BV 380 breed
-

Source Tissue

Source Tissue Comment Organism Textmining
gastrointestinal tract
-
 Gallus gallus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 the adenosine deaminase activity level is highest at day 1 in all the regions of chicken gastrointestinal tract and could be reduced or enhanced by corticosterone and dibutyryl cAMP, respectively, in an age-specific manner Gallus gallus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxyadenosine + H2O
-
 Gallus gallus 2'-deoxyinosine + NH3
-
 ir
adenosine + H2O
-
 Gallus gallus inosine + NH3
-
 ir

Synonyms

Synonyms Comment Organism
ADA
-
 Gallus gallus
adenosine deaminase
-
 Gallus gallus