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Literature summary for 3.5.4.37 extracted from
- Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editing (2005), Science, 309, 1534-1539.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zinc | the structure reveals zinc in the active site | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P78563 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| hADAR2-D | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| Inositol hexakisphosphate | is buried within the enzyme core, contributing to the protein fold. Inositol hexakisphosphate is required for activity. Amino acids that coordinate inositol hexakisphosphate in the crystal structure are conserved in some adenosine deaminases that act on tRNA | Homo sapiens | |
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