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Literature summary for 3.5.4.37 extracted from

  • Dawson, T.R.; Sansam, C.L.; Emeson, R.B.
    Structure and sequence determinants required for the RNA editing of ADAR2 substrates (2004), J. Biol. Chem., 279, 4941-4951.
    View publication on PubMed
Search for more literature for 3.5.4.37

Cloned(Commentary)

Cloned (Comment) Organism
expression in Pichia pastoris Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
adenine in double-stranded RNA + H2O Rattus norvegicus the enzyme is involved in involved in the editing of mammalian RNAs by the site-specific conversion of adenosine to inosine hypoxanthine in double-stranded RNA + NH3
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenine in double-stranded RNA + H2O the enzyme is involved in involved in the editing of mammalian RNAs by the site-specific conversion of adenosine to inosine Rattus norvegicus hypoxanthine in double-stranded RNA + NH3
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 ?
adenine in double-stranded RNA + H2O editing frequency in rADAR2 pre-mRNA. Both sequence and structural elements are required to define adenosine moieties targeted for specific ADAR2-mediated deamination Rattus norvegicus hypoxanthine in double-stranded RNA + NH3
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 ?

Synonyms

Synonyms Comment Organism
ADAR2
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8
-
 assay at Rattus norvegicus