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Literature summary for 3.5.4.17 extracted from

  • Uchida, H.; Chen, Y.X.; Nagai, H.; Fujisaki, Y.; Harihara, K.; Saka, N.; Kugisaki, Y.; Nomura, A.
    Distribution of adenosine (phosphate) deaminases with unusual substrate specificity in marine mollusc (1998), Comp. Biochem. Physiol. B, 119, 227-233.
No PubMed abstract available

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.065
-
2',3'-Cyclic AMP
-
Turbo cornutus
0.067
-
3'-deoxyadenosine
-
Turbo cornutus
0.067
-
adenosine 3'-phenylphosphonate
-
Turbo cornutus
0.071
-
2'-deoxyadenosine
-
Turbo cornutus
0.075
-
adenosine
-
Turbo cornutus
0.085
-
3'-AMP
-
Turbo cornutus
0.094
-
adenosine
-
Meretrix lusoria
0.11
-
3'-AMP
-
Meretrix lusoria
0.12
-
adenosine 3'-phenylphosphonate
-
Meretrix lusoria
0.13
-
2',3'-cAMP
-
Meretrix lusoria
0.65
-
5'-deoxyadenosine
-
Turbo cornutus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
64000
-
2 * 64000, SDS-PAGE Turbo cornutus
140000
-
gel filtration Turbo cornutus

Organism

Organism UniProt Comment Textmining
Meretrix lusoria
-
-
-
Turbo cornutus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Turbo cornutus
partial Meretrix lusoria

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.77
-
-
Meretrix lusoria
126
-
-
Turbo cornutus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2',3'-cAMP + H2O
-
Meretrix lusoria 2',3'-cIMP + NH3
-
?
2',3'-cAMP + H2O
-
Turbo cornutus 2',3'-cIMP + NH3
-
?
2'-deoxyadenosine + H2O
-
Turbo cornutus 2'-deoxyinosine + NH3
-
?
3'-AMP + H2O
-
Meretrix lusoria 3'-IMP + NH3
-
?
3'-AMP + H2O
-
Turbo cornutus 3'-IMP + NH3
-
?
3'-deoxyadenosine + H2O
-
Turbo cornutus 3'-deoxyinosine + NH3
-
?
5'-AMP + H2O
-
Meretrix lusoria 5'-IMP + NH3
-
?
5'-AMP + H2O no activity Turbo cornutus 5'-IMP + NH3
-
?
5'-deoxyadenosine + H2O
-
Turbo cornutus 5'-deoxyinosine + NH3
-
?
adenosine + H2O
-
Meretrix lusoria inosine + NH3
-
?
adenosine + H2O
-
Turbo cornutus inosine + NH3
-
?
adenosine 3'-phenyl phosphonate + H2O
-
Meretrix lusoria inosine 3'-phenylphosphonate + NH3
-
?
adenosine 3'-phenyl phosphonate + H2O
-
Turbo cornutus inosine 3'-phenylphosphonate + NH3
-
?
ADP + H2O no activity Meretrix lusoria IDP + NH3
-
?
ADP + H2O no activity Turbo cornutus IDP + NH3
-
?
ATP + H2O no activity Meretrix lusoria ITP + NH3
-
?
ATP + H2O no activity Turbo cornutus ITP + NH3
-
?

Subunits

Subunits Comment Organism
dimer 2 * 64000, SDS-PAGE Turbo cornutus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4 4.5 deamination of 3'-AMP Meretrix lusoria
4 4.5 deamination of 3'-AMP Turbo cornutus
4.5 6.5 deamination of 3',5'-cAMP, ADP and ATP Turbo cornutus
4.5 6.5 deamination of adenosine, 2',3'-cyclic AMP and adenosine 3'-phenylphosphonate Meretrix lusoria

pH Range

pH Minimum pH Maximum Comment Organism
3.5 6.5 pH 3.5: about 65% of maximal activity, pH 6.5: about 40% of maximal activity, deamination of adenosine 3'-phenylphosphonate. pH 3.5: about 55% of maximal activity, pH 6.5: about 25% of maximal activity, deamination of 2',3'-cyclic AMP Turbo cornutus