Activating Compound | Comment | Organism | Structure |
---|---|---|---|
H2O2 | 0.1 mM H2O2 is the optimum concentration for the activation of GTPCHI | Homo sapiens | |
L-phenylalanine | feedback regulation via L-phenylalanine | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
H2O2 | more than 0.3 mM H2O2 result in a decrease in activity of GTPCHI, the function of the GTP cyclohydrolase I/GTP cyclohydrolase I feedback regulatory protein complex is not affected by H2O2 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epidermis | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Homo sapiens | formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GTP cyclohydrolase I | - |
Homo sapiens |
GTPCHI | - |
Homo sapiens |