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Literature summary for 3.5.4.10 extracted from

  • Penuelas, S.; Noe, V.; Ciudad, C.J.
    Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells (2005), FEBS J., 272, 696-710.
    View publication on PubMed

Application

Application Comment Organism
medicine determination of differentially expressed genes in HT-29 cells, both after short treatment with methotrexate and after the resistance to methotrexate has been established. Enzyme as well as survivin and inosine monophosphate dehydrogenase type II are upregulated Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P31939
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Source Tissue

Source Tissue Comment Organism Textmining
HT-29 cell
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Homo sapiens
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