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Literature summary for 3.5.4.10 extracted from

  • Ni, L.; Guan, K.; Zalkin, H.; Dixon, J.D.
    De novo purine biosynthesis: cloning, sequencing and expression of a chicken PurH cDNA encoding 5-aminoimidazole-4-carboxamide-ribinucleotide transformylase-IMP cyclohydrolase (1981), Gene, 106, 197-205.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Gallus gallus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
64422
-
2 * 64422, open reading frame, gel filtration Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide Gallus gallus de novo purine synthesis step 10 ?
-
?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
expressed as glutathione-S-transferase fusion protein in Escherichia coli mutants Gallus gallus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide
-
Gallus gallus IMP + H2O
-
ir
5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide de novo purine synthesis step 10 Gallus gallus ?
-
?

Subunits

Subunits Comment Organism
dimer 2 * 64422, open reading frame, gel filtration Gallus gallus