Literature summary for 3.5.3.7 extracted from

Romagnoli, G.; Verhoeven, M.D.; Mans, R.; Fleury Rey, Y.; Bel-Rhlid, R.; van den Broek, M.; Seifar, R.M.; Ten Pierick, A.; Thompson, M.; Mueller, V.; Wahl, S.A.; Pronk, J.T.; Daran, J.M.
An alternative, arginase-independent pathway for arginine metabolism in Kluyveromyces lactis involves guanidinobutyrase as a key enzyme (2014), Mol. Microbiol., 93, 369-389.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Saccharomyces cerevisiae	Kluyveromyces lactis
expressed in Saccharomyces cerevisiae	no activity in Kluyveromyces lactis strain GG1632

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4-guanidinobutanoate + H2O	Kluyveromyces lactis	-	4-aminobutanoate + urea	-	?
4-guanidinobutanoate + H2O	Kluyveromyces lactis IMS0367	-	4-aminobutanoate + urea	-	?

Organism

Organism	UniProt	Comment	Textmining
Kluyveromyces lactis	-	-	-
Kluyveromyces lactis IMS0367	-	-	-
no activity in Kluyveromyces lactis strain GG1632	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-guanidinobutanoate + H2O	-	Kluyveromyces lactis	4-aminobutanoate + urea	-	?
4-guanidinobutanoate + H2O	-	Kluyveromyces lactis IMS0367	4-aminobutanoate + urea	-	?

Synonyms

Synonyms	Comment	Organism
GBU1	-	Kluyveromyces lactis
guanidinobutyrase	-	Kluyveromyces lactis

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Release 2023.1 (January 2023)