Literature summary for 3.5.3.6 extracted from

Trejo-Soto, P.J.; Aguayo-Ortiz, R.; Yepez-Mulia, L.; Hernandez-Campos, A.; Medina-Franco, J.L.; Castillo, R.
Insights into the structure and inhibition of Giardia intestinalis arginine deiminase homology modeling, docking, and molecular dynamics studies (2016), J. Biomol. Struct. Dyn., 34, 732-748 .

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Application

Application	Comment	Organism
drug development	the lack of this enzyme in the human host makes arginine deiminase an attractive target for drug design against Giardia intestinalis	Giardia intestinalis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-arginine + H2O	Giardia intestinalis	-	L-citrulline + NH3	-	?

Organism

Organism	UniProt	Comment	Textmining
Giardia intestinalis	Q27657	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-arginine + H2O	-	Giardia intestinalis	L-citrulline + NH3	-	?

Subunits

Subunits	Comment	Organism
homodimer	generation of a theoretical model of the homodimer 3D structure of the enzyme using computational techniques and homology modeling	Giardia intestinalis

General Information

General Information	Comment	Organism
physiological function	the enzyme is involved in the energy production and defense of this protozoan parasite	Giardia intestinalis

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Release 2023.1 (January 2023)